/bastien

About bastien

This author has not yet filled in any details.
So far bastien has created 58 blog entries.

Mitochondrial dysfunction is not the initial cause of insulin resistance in skeletal muscle

juillet 2015|

Insulin resistance, a key metabolic disturbance of type 2 diabetes and obesity, has been associated with reduced lipid oxidation rates [...]

An APOA5 3′ UTR Variant Associated with Plasma Triglycerides Triggers APOA5 Downregulation by Creating a Functional miR-485-5p Binding Site.

juillet 2015|

APOA5 is a major actor of triglyceride rich lipoproteins (TGRL) metabolism, activating lipoprotein lipase activity and regulating TGRL hepatic clearance. [...]

Low-dose food contaminants trigger sex-specific, hepatic metabolic changes in the progeny of obese mice

juillet 2015|

Environmental contaminants are suspected to be involved in the epidemic incidence of metabolic disorders, food ingestion being a primarily route [...]

Anti-aggregatory properties of in vivo oxidized HDL: evidence from patients with abetalipoproteinemia

juillet 2015|

Many studies have shown that high-density lipoproteins (HDL) possess anti-atherogenic properties, including antioxidant and anti-thrombotic properties. There are few studies [...]

Modulating absorption and postprandial handling of dietary fatty acids by structuring fat in the meal: a randomized cross-over clinical trial

juillet 2015|

Prolonged postprandial hypertriglyceridemia is a potential risk factor for cardiovascular diseases. This is also associated in obese people with a [...]

Visceral Fat Accumulation During Lipid Overfeeding Is Related to Subcutaneous Adipose Tissue Characteristics in Healthy Men

juillet 2015|

The mechanisms governing the orientation of excess lipids toward ectopic sites, contributing to visceral adipose depots and insulin resistance are [...]

p-Cresyl Sulfate Promotes Insulin Resistance Associated with chronic kidney disease

juillet 2015|

The mechanisms underlying the insulin resistance that frequently accompanies chronic kidney disease (CKD) are poorly understood, but the retention of [...]

GPIHBP1 C89F neomutation and hydrophobic C-terminal domain G175R mutation in two pedigrees with severe hyperchylomicronemia

juillet 2015|

GPIHBP1 is a new endothelial binding site for lipoprotein lipase (LPL). We have identified two new missense mutations of the [...]

Characterization of the initial phase of subcutaneous adipose tissue remodeling and development during of weight gain in healthy subjects

juillet 2015|

We used experimental overfeeding as a unique situation to decipher the early processes occurring in adipose tissue during weight gain. [...]

Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes

juillet 2015|

Phospholipase D (PLD) is known to be involved in myogenesis, but its mechanism of action remains unclear. We thus investigated [...]