About vlarge

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So far vlarge has created 116 blog entries.

January 2018 – Teams 3, 2 et 5: ER-mitochondria miscommunication involved in muscle insulin resistance (Diabetes)

February 2018|

Skeletal muscle is the main tissue responsible for insulin-stimulated glucose uptake, so it plays a major role in regulating glycemia [...]

Oct 2017 – Team 2 :Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro. (PNAS)

October 2017|

Our experiments provide the analysis of lipid metabolite circadian oscillations in a cellular system synchronized in vitro, suggesting cell-autonomous diurnal [...]

July 2017 – Team 5 :Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties. (Cell Death and Differentiation)

July 2017|

  Mesenchymal stem cells (MSCs) protect tissues against cell death induced by ischemia/reperfusion insults. This therapeutic effect seems to be [...]

July 2017 – Team 1, 2, 3, 4 and 5 :EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease in severely obese people: do they lead to over-referral? (Diabetologia)

July 2017|

We aimed to assess the application of the recent European Association for the Study of the Liver (EASL)-European Association for [...]

June 2017 – Team 5 : Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice (EMBO Molecular Medicine)

June 2017|

PIKfyve is an evolutionarily conserved lipid kinase that regulates pleiotropic cellular functions. Here, we identify PIKfyve as a key regulator [...]

June 2017 – TEAMS 1, 2 and 3 : Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice (Nature Medicine)

June 2017|

  The endocrine-derived hormone fibroblast growth factor (FGF) 19 has recently emerged as a potential target for treating metabolic disease. [...]

April 2017- TEAM 4: Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia (New England J Medicine )

April 2017|

A protein that is expressed on capillary endothelial cells, called GPIHBP1 (glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1), binds lipoprotein lipase [...]

April 11, 2017

April 2017|

11 April: Séminar of Pr. BRAUN -Zurich (Suisse) […]

6-7 nov 2017: CarMeN co-organise le congrès FSEV

March 2017|

6-7 nov : Co-organisation of the congress  FSEV CarMeN laboratory will co-organise the first congress about extracellular vesicules (FSEV-2017, PARIS).   [...]


March 2017|

  July 2017 Low-dose pollutant mixture triggers metabolic disturbances in female mice leading to common and specific features as compared [...]