4 april 2018: Marie-Caroline Michalski (Team 4 CarMeN) on a television show “Enquête à la Une” on France 5
Marie-Caroline MICHALSKI, Team 4 leader was invited on a television show on France 5 called Enquête de santé about fat. [...]
March 2018 – Teams 1 and 4 : Skeletal muscle insulin resistance induced by the by-product of omega-3 fatty acid peroxidation 4-hydroxy-2-hexenal (4-HHE) (Diabetologia)
The work of Christophe Soulage from CarMeN team 3 in collaboration with the team 5, have just highlighted the role [...]
March 2018 – A new publication from Teams 3, 2 and 5 focussed by The INSERM and “Sciences et Avenir” journal
The new article " Tubbs E. et al. Diabetes 2018" from Teams 3, 2 and 5 focussed by the INSERM [...]
Janvier 2018 – un nouvel article dans “Diabetes” pour les Equipes 3, 2 et 5 de CarMeN / info relayée par l’INSERM
pour plus d'info: cliquez ici
January 2018 – Teams 3, 2 and 5: ER-mitochondria miscommunication involved in muscle insulin resistance (Diabetes)
Skeletal muscle is the main tissue responsible for insulin-stimulated glucose uptake, so it plays a major role in regulating glycemia [...]
nov. 2017: a new Review published in NJEM
Denis Fouque (CarMeN) published a revew in the famous New England Journal of Medicine. Revue title: "Nutritional Management of Chronic [...]
Oct 2017 – Team 2 :Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro. (PNAS)
Our experiments provide the analysis of lipid metabolite circadian oscillations in a cellular system synchronized in vitro, suggesting cell-autonomous diurnal [...]
July 2017 – Team 5 :Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties. (Cell Death and Differentiation)
Mesenchymal stem cells (MSCs) protect tissues against cell death induced by ischemia/reperfusion insults. This therapeutic effect seems to be [...]
July 2017 – Team 1, 2, 3, 4 and 5 :EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease in severely obese people: do they lead to over-referral? (Diabetologia)
We aimed to assess the application of the recent European Association for the Study of the Liver (EASL)-European Association for [...]
June 2017 – Team 5 : Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice (EMBO Molecular Medicine)
PIKfyve is an evolutionarily conserved lipid kinase that regulates pleiotropic cellular functions. Here, we identify PIKfyve as a key regulator [...]