Team 1 : “Nutritional Adaptations, Environment and Diabetes”

Nutritional Adaptations, Environment and Diabetes

To maintain homeostasis in normal range, all living species are able to develop appropriate responses to transient or sustained changes occuring in their direct environment. Humans, all life-long from embryo to elderly, are exposed to environmental modifications including lifestyle changes, nutritional habits or pollutant contaminations. Good health and long-life expectancy are thus strongly dependent on the ability to correctly adapt and respond to these modifications. It is now suspected that metabolic diseases, such as obesity, type 2 diabetes and their related complications, are linked to defects in these adaptive mechanisms.

The main objectives of Team 1 of CarMeN laboratory are to define the mechanisms involved in the physiological response to metabolic stress in humans, to identify potential defects in these processes and to develop new strategies to  fight metabolic and nutritional diseases. 

Our different research projects combine clinical investigations, studies with animal model and experimental research, based on nutrigenomics and epigenetics. They benefit from the close collaboration of scientists specialized in biochemistry, physiology, immunology, cellular and molecular biology and of clinicians from diabetology, metabolism, nutrition and nephrology.

Our Team is mainly located at the Faculty of Medicine Lyon-Sud and the Biochemistry department of Hospital Lyon-Sud in the vicinity of the Rhone-Alpes Research Center in Human Nutrition (CRNH-RA). Part of the team is located in IMBL at INSA Lyon.

Main research topics of Team 1

During the last decades, major modifications in our nutritional environment and eating behavior, have largely contributed to the observed overweight, obesity and diabetes epidemics. The main objectives of our research program are 1) to understand at the molecular level the adaptive responses to changes in our nutritional environment and 2) to identify the potential defects in these processes that could contribute to the metabolic pathologies. To this aim, we investigate the adaptive mechanisms to metabolic stress and pollutant exposure under different experimental conditions reflecting as much as possible normal life. Based on the significant advances made over the last years, our strategy rely on 5 complementary and connected research programs:

– “Metabolic adaptation and inflammation of fat tissues during overfeeding” to understand adipose tissue depots remodeling and to propose strategies to fight obesity and prevent its complications;

– «Adipose stem cells in healthy or pathological adipose tissues» to understand the  mechanisms initiating adipose tissue alterations and inflammation which lead to the complications of obesity;

– “Metabolic disrupters: impact of environmental pollutants in metabolic diseases” to unravel the contribution and the mechanisms of action of pollutants in triggering or amplifying metabolic diseases;

– “Metabolic adaptations in chronic kidney disease” to define the determinants of metabolic complications, especially insulin resistance, in chronic kidney disease and provide new treatments;

– “Probiotics as a new strategy to fight metabolic diseases” to demonstrate that selected bacterial strains can be powerful agents to treat obese and diabetic patients

Main technical  approaches and tools

Nutritional studies in humans in the Research Center for Human Nutrition CRNH-RA. Measurement of insulin sensitivity (hyperinsulinemic euglycemic clamp) / Human tissue resources (muscle and adipose tissue) / Animal models (mice) / Cell culture (stem cells, adipocytes, muscle cells) / Genomics and epigenetics (DNA arrays, RT-qPCR) / Intracellular signaling studies (insulin) / Adipocyte size measurement / Immunocytology / In vitro utilization of adenovirus or shRNA

 

 

Topic 1 : Metabolic adaptation and inflammation of fat tissues during oveequipe1_fig3rfeeding

Excess calorie intake, exceeding energy expenditure, is one of the characteristics of the modern life and largely contributes to the development of obesity. The mechanisms responsible for the metabolic orientation of energy between storage and catabolism in vivo during overfeeding are not known. In collaboration with the CRNH-RA, we are developing an ambitious research program to characterize these mechanisms usinga overfeeding protocols in humans and in animal models.

In the clinical studies, volunteers (lean and overweight subjects) are submitted to an overfeeding protocol during which they receive about 30% calorie excess each day for several weeks. A detailed analysis of biological, metabolic and anthropometric modifications is performed during the protocol. Several protocols are conducted with different types of supplementation (lipids, fructose or junk food). We are also testing new strategies to prevent the deleterious effects of overfeeding (polyphenols, probiotics). Important results have been already obtained to allow understanding the mechanisms of fuel partitioning in skeletal muscle and the first steps of adipose tissue development when people are gaining weight (Seyssel et al, JCEM, 20145; Alligier et al JCEM, 2012).

Interestingly, some subjects show a preferred orientation of lipid storage in visceral adipose tissue and other ectopic depots such as liver and muscle. This suggests that these subjects probably display a higher risk for the development of metabolic syndrome. We are currently investigating in more details these subjects with the objective of identifying novel risk biomarkers using transcriptomic approach in adipose tissue and skeletal muscle and a metabolomics approach in blood and urine. Parallel to the clinical studies, fat accumulation mechanisms and functions of adipocytes are studied in vitro using human adipocytes in primary culture.

 

 

Topic 2 : Adipose stem cells in healthy or pathological adipose tissues

Adipose tissue-derived mesenchymal stem cells (Adipose Stem Cells, ASC), present in large numbers in adipose tissue, not only have the ability to differentiate into adipocytes, but also have many regulatory functions in particular with respect to immune cells. We explore the contribution of these cells to adipose tissue functions and its pathological changes across different lines of research.

One research axis, developed by A. El Jaafari and L. Pirola, is devoted to the understanding of inflammation in adipose tissue. While the well documented presence of macrophages in adipose tissue have been shown to contribute to the low grade inflammation associated with obesity, we have recently involved 2 new players in this process:  the adipose-derived mesenchymal stem cells (ASC) and the Th17-lymphocytes (El Jaafari et al, Diabetes, 2015). We have demonstrated that ASC harvested from the adipose tissue of obese individuals (but not from lean donors) can increase IL-17A and IL-1beta secretion by blood mononuclear cells. In turn these cytokines inhibit adipogenesis and reduce insulin action in mature adipocytes. This opens new fields of research to understand the mechanisms of adipose tissue inflammation during weight gain. Because interactions of ASC with Th17 lymphocytes appear to mainly involve cell-cell contact, our goal now is to identify the molecules implicated in these interactions, including the antigens, which might be presented by ASC to Th17 lymphocytes.

Another research project, developed by A. Mey, seeks to understand the origin of the functional differences between the fat depots and their contributions to obesity. She investigates the molecular and biological characteristics of the adipose mesenchymal stem cells (ASC) which contribute to the developmental origin of these depots and remain present in the tissues in adulthood. To understand how the nutritional environment impacts the properties of the ASC at different periodes of life, we have developed the isolation and culture of these cells from different adipose tissue depots in mice and humans.

An interesting property of the ASC is the possibility, as stem cells, to be differentiated in different cell types. We have developed a protocol to generate beta-pancreatic-like cells from human-derived ASC. We will now use these cells to study the impact of ASC-mediated inflammation on beta-cell generation and function in order to better understand the mechanisms leading to beta-cell dysfunction in type-2 diabetes. We also hope to optimize the production of beta-like cells from ASC to propose in the future these cells as therapeutic tools. This will be performed by A. El Jaafari in collaboration with members of team 3 (A-M Madec and C. thivolet) and of the Cell Therapy Unit of Lyon Hospital who recently joined team 1.

 

 

Topic 3 : Metabolic disrupters

Apart from genetics, excess calories and lack of physical activity, it is known that environmental pollutants, specifically those endowed with hormonal disrupting activities and acting at low dosage (i.e., the endocrine disruptors), contribute to the epidemic of metabolic disorders. Several epidemiological studies have shown a significant correlation between criteria of the metabolic syndrome and the presence in the blood or urine of pollutants or their metabolites. In addition, experimental studies in rodents, including works from our team (Naville et al, FASEB J, 2013; PLOSOne, 2015; Ruzzin et al, EHP, 2011) established a causal relationship between exposure to chemicals and obesity-related metabolic dysfunctions, such as insulin resistance. Because of the high vulnerability of embryos and newborns, D. Naville and B. Le Magueresse in the team, have developped a model of exposure to very low doses of a cocktail of pollutants (dioxins, PCB153, DEHP and BPA) added to a high-fat high sucrose diet and provide to mice dams and then to their progeny. Changes in biological parameters, fat mass measurement, glucose tolerance and insulin sensitivity tests in the progeny (F1 and after) are studied. Molecular mechanisms are as well investigated both using a candidate-gene approach and a transcriptomic large approach to identify specific genes and pathways leading to the observed metabolic disturbances.

We are also exploring the phenotype of PXR KO mice in collaboration with the group of J. Ruzzin, Bergen University, Norway. Besides, taking into account the crutial role of gut in metabolic health, we make the hypothesis that variations in microbiota may alter the way individuals metabolize and respond to pollutants and we will also test whether interventions on microbiota hold the potential to offer protection from the adverse effects of pollutants.

 

 

Topic  4 : Metabolic adptations in chronique kidney disease

Chronic kidney disease (CKD) is frequently associated with peripheral insulin resistance, which is a major cardiovascular risk factor. However, the reasons why CKD patients so often develop insulin resistance, even in absence of overweight or obesity, are largely unknown.

D. Fouque and Ch. Soulage in the team recently demonstrated that the accumulation of uremic toxins, such as p-cresol, in end-stage renal disease could be a key factor for the development of insulin resistance (Koppe et al. Amer Soc Nephrol, 2013). Using mouse model of CKD, we are currently extend this concept to other uremic toxins, like endoxyl sulfate, and try to define their mechanisms of action, focusing on the activation of nuclear receptors, such as arylhydrocarbon receptor (AhR, i.e. the nuclear receptor of dioxins). The mechanisms underlying the development of insulin resistance will be investigated in vitro using adipocytes and muscle cells in culture incubated with uremic toxins. Identifications of the pathways mediating the deleterious effects of these compounds and the potential role of AhR will be explored in details in these in vitro systems. We will then further explore the relevance of the findings in our cohort of patients with CKD. The role of the intestinal flora will also be investigated with the aim of elaborating pro/pre-biotics strategies to modulate the production of uremic toxins.

Other research projects include the study of the impact of peritoneal dialysis on intra-abdominal white adipose tissue functions using an original mouse model of peritoneal dialysis under development in the laboratory. The relevance of this pre-clinical model will be assessed in subcutaneous and omental adipose tissue biopsies from patients treated by peritoneal dialysis in which we will analyse fat cell size, histology (immune cell infiltration, fibrosis), adipocyte functions and adipokine secretion in relation to glucose exposure, peritoneal transport type and metabolic risk factors.

 

Topic  5 : Probiotics as a new stategy to fight metabolic diseases

The use of probiotics with the aim of modulating blood glucose and hence improving diabetes has been envisaged for a long time, particularly as nutritional supplements, but the discovery of the critical role of gut microbiota in metabolic diseases has logically boosted research efforts in this field. Obesity and type 2 diabetes are indeed associated with perturbation of the composition and function of the gut microbiota (called dysbiosis), globally characterized by change in the ratio between Firmicutes (Gram-positive) and Bacteroidetes (Gram-negative), the two major phyla in the gut. Furthermore, it has been recently demonstrated that the gut microbiota certainly plays a critical role in the pathogenesis of these diseases. Several bacterial strains, used as probiotics, have recently shown clear beneficial actions on glucose tolerance and insulin sensitivity in mouse models. However, the effects are less important in humans and their mechanisms of action only partly defined. Our goal is therefore to identify potent bacterial strains with strong beneficial effects for human health and to propose them as new  probiotics for metabolic diseases prevention and/or treatment.

To identify these new strains, we are working in close collaboration with the IGFL team of F. Leulier (a leader in the field of host-bacteria interactions in drosophila) (mettre le lien: http://igfl.ens-lyon.fr/equipes/f.-leulier-functional-genomics-of-host-intestinal-bacteria-interactions) who has developed an innovative screening system to qualify Lactobacillus strains with anti-diabetic properties (under patenting).

 

We recently used together a variant of this powerful screening system for functional strain qualification to demonstrate for the first time the critical role of microbiota and of a selected L.plantarum strain in the juvenile growth (Schwarzer et al. Science 2016). We are currently qualifying relevant strains for their anti-diabetic properties in diabetic mice, as a pre-clinical test before their evaluation in patients. In parallel, as indicated in the Topics 2 and 3 before, bacterial strains with probiotic properties are also evaluated for their potential to buffer the toxic effects of a cocktail of pollutants in exposed mice and to control the production of uremic toxins in a model of mouse with chronic kidney disease.

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Team 1 Leaders
VIDAL Hubert DR1 hubert.vidal@univ-lyon1.fr
 LAVILLE Martine DR1 martine.laville@univ-lyon1.fr
 

Members
BENOIT Julien PhD benoit.julien@univ-lyon1.fr
BERGER-DANTY Emmanuelle CR1 emmanuelle.danty@univ-lyon1.fr
CHARRIE Anne MCUPH anne.charrie@univ-lyon1.fr
DA SILVA Joao Henriq Postdoctorant joaohenriq@hotmail.com
DISSE Emmanuel PUPH emmanuel.disse@chu-lyon.fr
DRAI Jocelyne PH jocelyne.drai@chu-lyon.fr
DURAND Christine TR christine2.durand@inserm.fr
ELJAAFARI Assia PH assia.eljaafari@univ-lyon1.fr
FALANDRY Claire PUPH claire.falandry@chu-lyon.fr
FOUQUE Denis PUPH denis.fouque@chu-lyon.fr
GELOEN Alain DR2 alain.geloen@insa-lyon.fr
GERARD Céline Postdoctorante celine.gerard@inserm.fr
GOUDABLE Joëlle PUPH joelle.goudable@univ-lyon1.fr
HOIBIAN Elsa PhD elsa.hoibian@insa-lyon.fr
JOBEILI Lara PhD lara.jobeili@gmail.com
JULIEN Benoit PhD benoit.julien@univ-lyon1.fr
KAISERLIAN Dominique DR1 dominique.kaiserlian@inserm.fr
LE MAGUERESSE Brigitte DR2 brigitte.lemagueresse@inserm.fr
LEFEVRE Camille PhD camille.lefevre@etu.univ-lyon1.fr
MEUGNIER Emmanuelle IR emmanuelle.meugnier@univ-lyon1.fr
MEY Anne CR1 anne.mey@inra.fr
MOJALLAL Alain-Ali PUPH dr.mojallal@gmail.com
NATAF Serge PUPH serge.nataf@chu-lyon.fr
NAVILLE Danielle CR1 danielle.naville@inserm.fr
NAZARE Julie-Anne MCU julie-anne.nazare@univ-lyon1.fr
PAYS Laurent MCU laurent.pays@univ-lyon1.fr
PELLETIER Caroline PhD c.pelletier.5@gmail.com
PINTEUR Claudie TR claudie.pinteur@inserm.fr
PIROLA Luciano CR1 luciano.pirola@univ-lyon1.fr
PUGEAT Michel PUPH émérite michel.pugeat@chu-lyon.fr
SEGRESTIN Bérénice PhD berenice.segrestin@gmail.com
SOULAGE Christophe MCU christophe.soulage@insa-lyon.fr
VEGA Nathalie TR nathalie.vega@univ-lyon1.fr

2018 (january-june)

  1. Yi, D., Monteiro, E. B., Chambert, S., Soula, H. A., Daleprane, J. B. and Soulage, C. O. (2018). Determination of the binding properties of p-cresyl glucuronide to human serum albumin Biochimie 150 1-7 10.1016/j.biochi.2018.04.019
  2. Wojtala, M., Macierzynska-Piotrowska, E., Rybaczek, D., Pirola, L. and Balcerczyk, A. (2018).  Pharmacological and transcriptional inhibition of the G9a histone methyltransferase suppresses proliferation and modulates redox homeostasis in human microvascular endothelial cells Pharmacological Research 128 252-263 10.1016/j.phrs.2017.10.014
  3. Tubbs, E., Chanon, S., Robert, M., Bendridi, N., Bidaux, G., Chauvin, M. A., Jingwei, J. C., Durand, C., Gauvrit-Ramette, D., Vidal, H., Lefai, E. and Rieusset, J. (2018) Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans Diabetes 67 636-650 10.2337/db17-0316
  4. Stockler-Pinto, M. B., Soulage, C. O., Borges, N. A., Cardozo, L., Dolenga, C. J., Nakao, L. S., Pecoits-Filho, R., Fouque, D. and Mafra, D. (2018) From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-kappaB/Nrf2 expression Int Urol Nephrol 50 347-354 10.1007/s11255-017-1748-y
  5. Soulere, L., Alix, P. M., Croze, M. L. and Soulage, C. O. (2018) Identification of novel antilipogenic agents targeting fatty acid biosynthesis through structure-based virtual screening Chemical Biology & Drug Design 92 1366-1372 10.1111/cbdd.13202
  6. Soulage, C. O., Puig, L. S., Soulere, L., Zarrouki, B., Guichardant, M., Lagarde, M. and Pillon, N. J. (2018) Skeletal muscle insulin resistance is induced by 4-hydroxy-2-hexenal, a by-product of n-3 fatty acid peroxidation Diabetologia 61 688-699 10.1007/s00125-017-4528-4
  7. Snoek, H. M., Eijssen, L. M. T., Geurts, M., Vors, C., Brown, K. A., Bogaardt, M. J., Dhonukshe-Rutten, R. A. M., Evelo, C. T., Fezeu, L. K., Finglas, P. M., Laville, M., Ocke, M., Perozzi, G., Poppe, K., Slimani, N., Tetens, I., Timotijevic, L., Zimmermann, K. and van’t Veer, P. (2018) Advancing food, nutrition, and health research in Europe by connecting and building research infrastructures in a DISH-RI: Results of the EuroDISH project Trends in Food Science & Technology 73 58-66 10.1016/j.tifs.2017.12.015
  8. Sigaux, N., Ganry, L., Mojallal, A., Breton, P. and Bouletreau, P. (2018) Stereophotogrammetry and facial surgery: Principles, applications and prospects Annales De Chirurgie Plastique Esthetique 63 62-68 10.1016/j.anplas.2017.07.006
  9. Rovere, M. R., Rousselle, P., Haftek, M., Charleux, B., Kocaba, V., Auxenfans, C., Nataf, S. and Damour, O. (2018) Preserving Basement Membranes during Detachment of Cultivated Oral Mucosal Epithelial Cell Sheets for the Treatment of Total Bilateral Limbal Stem Cell Deficiency Cell Transplantation 27 264-274 10.1177/0963689717741140
  10. Roucher-Boulez, F., de la Perriere, A. B., Jacquez, A., Chau, D., Guignat, L., Vial, C., Morel, Y., Nicolino, M., Raverot, G. and Pugeat, M. (2018) Triple-A syndrome: a wide spectrum of adrenal dysfunction European Journal of Endocrinology 178 199-207 10.1530/eje-17-0642
  11. Reynaud, Q., Rabilloud, M., Roche, S., Poupon-Bourdy, S., Iwaz, J., Nove-Josserand, R., Blond, E., Laville, M., Llerena, C., Quetant, S., Reix, P., Touzet, S. and Durieu, I. (2018) Glucose trajectories in cystic fibrosis and their association with pulmonary function Journal of Cystic Fibrosis 17 400-406 10.1016/j.jcf.2017.09.010
  12. Pugeat, M., Plotton, I., de la Perriere, A. B., Raverot, G., Dechaud, H. and Raverot, V. (2018) Hyperandrogenic states in women: pitfalls in laboratory diagnosis European Journal of Endocrinology 178 R141-R154 10.1530/eje-17-0776
  13. Puertas, R. D., Jalabert, A., Meugnier, E., Euthine, V., Chevalier, P. and Rome, S. (2018) Analysis of the microRNA signature in left atrium from patients with valvular heart disease reveals their implications in atrial fibrillation Plos One 13 20 10.1371/journal.pone.0196666
  14. Perier-Muzet, M., Gatt, E., Peron, J., Falandry, C., Amini-Adle, M., Thomas, L., Dalle, S. and Boespflug, A. (2018) Association of Immunotherapy With Overall Survival in Elderly Patients With Melanoma Jama Dermatology 154 82-87 10.1001/jamadermatol.2017.4584
  15. Neto, M. P. C., Aquino, J. D., da Silva, L. D. R., Silva, R. D., Guimaraes, K. S. D., de Oliveira, Y., de Souza, E. L., Magnani, M., Vidal, H. and Alves, J. L. D. (2018) Gut microbiota and probiotics intervention: A potential therapeutic target for management of cardiometabolic disorders and chronic kidney disease? Pharmacological Research 130 152-163 10.1016/j.phrs.2018.01.020
  16. Metzger, M., Yuan, W. L., Haymann, J. P., Flamant, M., Houillier, P., Thervet, E., Boffa, J. J., Vrtovsnik, F., Froissart, M., Bankir, L., Fouque, D., Stengel, B. and NephroTest Study, G. (2018) Association of a Low-Protein Diet With Slower Progression of CKD Kidney International Reports 3 105-114 10.1016/j.ekir.2017.08.010
  17. Martin, K. A., Anderson, R. R., Chang, R. J., Ehrmann, D. A., Lobo, R. A., Murad, M. H., Pugeat, M. M. and Rosenfield, R. L. (2018) Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society* Clinical Practice Guideline Journal of Clinical Endocrinology & Metabolism 103 1233-1257 10.1210/jc.2018-00241
  18. Luce, M., Bouchara, A., Pastural, M., Granjon, S., Szelag, J. C., Laville, M., Arkouche, W., Fouque, D., Soulage, C. O. and Koppe, L. (2018) Is 3-Carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) a Clinically Relevant Uremic Toxin in Haemodialysis Patients? Toxins 10 16 10.3390/toxins10050205
  19. Leger, T., Hininger-Favier, I., Capel, F., Geloen, A., Rigaudiere, J. P., Jouve, C., Pitois, E., Pineau, G., Vaysse, C., Chardigny, J. M., Michalski, M. C., Malpuech-Brugere, C. and Demaison, L. (2018) Dietary canolol protects the heart against the deleterious effects induced by the association of rapeseed oil, vitamin E and coenzyme Q10 in the context of a high-fat diet Nutrition & Metabolism 15 14 10.1186/s12986-018-0252-4
  20. Le Saux, O. and Falandry, C. (2018) Is There an Age Threshold for Holding Off on Testing Novel Therapies? Current Oncology Reports 20 7 10.1007/s11912-018-0663-4
  21. Le Saux, O. and Falandry, C. (2018) Toxicity of Cancer Therapies in Older Patients Current Oncology Reports 20 11 10.1007/s11912-018-0705-y
  22. Kopple, J. D. and Fouque, D. (2018) Con: The role of diet for people with advanced Stage 5 CKD Opponent’s comments Nephrology Dialysis Transplantation 33 384-387 10.1093/ndt/gfx294a
  23. Kopple, J. D. and Fouque, D. (2018) Pro: The rationale for dietary therapy for patients with advanced chronic kidney disease Nephrology Dialysis Transplantation 33 373-378 10.1093/ndt/gfx333
  24. Koppe, L., Fouque, D. and Soulage, C. O. (2018) The Role of Gut Microbiota and Diet on Uremic Retention Solutes Production in the Context of Chronic Kidney Disease Toxins 10 12 10.3390/ toxins10040155
  25. Kalantar-Zadeh, K. and Fouque, D. (2018) Nutritional Management of Chronic Kidney Disease REPLY New England Journal of Medicine 378 584-585 10.1056/NEJMc1715765
  26. Julien, B., Pinteur, C., Vega, N., Labaronne, E., Vidal, H., Naville, D. and Le Magueresse-Battistoni, B. (2018) Evidence for estrogeno-mimetic effects of a mixture of low-dose pollutants in a model of ovariectomized mice Environmental Toxicology and Pharmacology 57 34-40 10.1016/ j.etap.2017.11.008
  27. Jouvene, C., Fourmaux, B., Geloen, A., Balas, L., Durand, T., Lagarde, M., Letisse, M. and Guichardant, M. (2018) Ultra-Performance Liquid Chromatography-Mass Spectrometry Analysis of Free and Esterified Oxygenated Derivatives from Docosahexaenoic Acid in Rat Brain Lipids 53 103-116 10.1002/lipd.12006
  28. Iceta, S., Disse, E. and Robert, M. (2018) Are we really assessing safety and efficacy of bariatric surgery in patients suffering from bipolar disorder? Surgery for Obesity and Related Diseases 14 723-724 10.1016/j.soard.2018.01.037
  29. Hoibian, E., Florens, N., Koppe, L., Vidal, H. and Soulage, C. O. (2018) Distal Colon Motor Dysfunction in Mice with Chronic Kidney Disease: Putative Role of Uremic Toxins Toxins 10 15 10.3390/toxins10050204
  30. Haution-Bitker, M., Gilbert, T., Vignoles, A., Lecardonnel, C., Watelet, S., Blond, E., Drai, J. and Bonnefoy, M. (2018) Associations between Plasmatic Polyunsaturated Fatty Acids Concentrations and Cognitive Status and Decline in Neurocognitive Disorders Journal of Nutrition Health & Aging 22 718-725 10.1007/s12603-018-1010-z
  31. Florens, N., Yi, D., Juillard, L. and Soulage, C. O. (2018) Using binding competitors of albumin to promote the removal of protein-bound uremic toxins in hemodialysis: Hope or pipe dream? Biochimie 144 1-8 10.1016/j.biochi.2017.09.018
  32. Falandry, C., Krakowski, I., Cure, H., Carola, E., Soubeyran, P., Guerin, O., Gaudin, H. and Freyer, G. (2018) Impact of geriatric assessment for the therapeutic decision-making of breast cancer: results of a French survey. AFSOS and SOFOG collaborative work Breast Cancer Research and Treatment 168 433-441 10.1007/s10549-017-4607-8
  33. Duhamel, M., Rose, M., Rodet, F., Murgoci, A. N., Zografidou, L., Regnier-Vigouroux, A., Vanden Abeele, F., Kobeissy, F., Nataf, S., Pays, L., Wisztorski, M., Cizkova, D., Fournier, I. and Salzet, M. (2018) Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies Molecular & Cellular Proteomics 17 1126-1143 10.1074/mcp.RA117.000443
  34. Chauveau, P., Aparicio, M., Bellizzi, V., Campbell, K., Hong, X., Johansson, L., Kolko, A., Molina, P., Sezer, S., Wanner, C., ter Wee, P. M., Teta, D., Fouque, D., Carrero, J. J. and European Renal Nutr, E. R. N. W. (2018) Mediterranean diet as the diet of choice for patients with chronic kidney disease Nephrology Dialysis Transplantation 33 725-735 10.1093/ndt/gfx085
  35. Capel, F., Geloen, A., Vaysse, C., Pineau, G., Demaison, L., Chardigny, J. M., Michalski, M. C. and Malpuech-Brugere, C. (2018) Rapeseed oil fortified with micronutrients can reduce glucose intolerance during a high fat challenge in rats Nutrition & Metabolism 15 12 10.1186/s12986-018-0259-x
  36. Burton, K. J., Pimentel, G., Zangger, N., Vionnet, N., Drai, J., McTernan, P. G., Pralong, F. P., Delorenzi, M. and Vergeres, G. (2018) Modulation of the peripheral blood transcriptome by the ingestion of probiotic yoghurt and acidified milk in healthy, young men Plos One 13 24 10.1371/journal.pone.0192947
  37. Bougaret, L., Delort, L., Billard, H., Le Huede, C., Boby, C., De la Foye, A., Rossary, A., Mojallal, A., Damour, O., Auxenfans, C., Vasson, M. P. and Caldefie-Chezet, F. (2018) Adipocyte/breast cancer cell crosstalk in obesity interferes with the anti-proliferative efficacy of tamoxifen Plos One 13 14 10.1371/journal.pone.0191571
  38. Borges, N. A., Carmo, F. L., Stockler-Pinto, M. B., de Brito, J. S., Dolenga, C. J., Ferreira, D. C., Nakao, L. S., Rosado, A., Fouque, D. and Mafra, D. (2018) Probiotic Supplementation in Chronic Kidney Disease: A Double-blind, Randomized, Placebo-controlled Trial Journal of Renal Nutrition 28 28-36 10.1053/j.jrn.2017.06.01
  39. Bonnefond-Ortega, M., Goudable, J., Chambrier, C. and Betry, C. (2018) Intestinal absorption of water-soluble and fat-soluble vitamins in clinical practice Nutrition Clinique Et Metabolisme 32 57-66 10.1016/j.nupar.2017.09.00
  40. Anjos, J. S., Cardozo, L., Esgalhado, M., Lindholm, B., Stenvinkel, P., Fouque, D. and Mafra, D. (2018) Could Low-Protein Diet Modulate Nrf2 Pathway in Chronic Kidney Disease? Journal of Renal Nutrition 28 229-234 10.1053/j.jrn.2017.11.005

2017

  1. Adrait, A., Perrot, X., Nguyen, M. F., Gueugnon, M., Petitot, C., Collet, L., Roux, A., Bonnefoy, M. and Grp, A. S. (2017) Do Hearing Aids Influence Behavioral and Psychological Symptoms of Dementia and Quality of Life in Hearing Impaired Alzheimer’s Disease Patients and Their Caregivers? Journal of Alzheimers Disease 58 109-121
  2. Andrieu, S., Guyonnet, S., Coley, N., Cantet, C., Bonnefoy, M., Bordes, S., Bories, L., Cufi, M. N., Dantoine, T., Dartigues, J. F., Desclaux, F., Gabelle, A., Gasnier, Y., Pesce, A., Sudres, K., Touchon, J., Robert, P., Rouaud, O., Legrand, P., Payoux, P., Caubere, J. P., Weiner, M., Carrie, I., Ousset, P. J., Vellas, B. and Grp, M. S. (2017) Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial Lancet Neurology 16 377-389
  3. Benoit B, Meugnier E, Castelli M, Chanon S, Vieille-Marchiset A, Durand C, Bendridi N, Pesenti S, Monternier PA, Durieux AC, Freyssenet D, Rieusset J, Lefai E, Vidal H, Ruzzin J. (2017) Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice. Nat Med 23; 990-996
  4. Blond, E., Disse, E., Cuerq, C., Drai, J., Valette, P. J., Laville, M., Thivolet, C., Simon, C. and Caussy, C. (2017) EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease in severely obese people: do they lead to over-referral? Diabetologia 60 1218-1222
  5. Bost, F., Chanon, S., Durand, C., Vieille-Marchiset, A., Robert, M., Dibner, C., Simon, C. and Lefai, E. (2017) Glucose Uptake Measurement and Response to Insulin Stimulation in In Vitro Cultured Human Primary Myotubes Sci Rep
  6. Caillet, P., Liuu, E., Simon, A. R., Bonnefoy, M., Guerin, O., Berrut, G., Lesourd, B., Jeandel, C., Ferry, M., Rolland, Y. and Paillaud, E. (2017) Association between cachexia, chemotherapy and outcomes in older cancer patients: A systematic review Clinical Nutrition 36 1473-1482
  7. Chanon, S., Durand, C., Vieille-Marchiset, A., Robert, M., Dibner, C., Simon, C. and Lefai, E. (2017) Glucose Uptake Measurement and Response to Insulin Stimulation in In Vitro Cultured Human Primary Myotubes Jove-Journal of Visualized Experiments
  8. Condello, G., Puggina, A., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Carlin, A., Simon, C., Ciarapica, D., Coppinger, T., Cortis, C., D’Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, A., Ling, F. C. M., Luzak, A., Napolitano, G., Nazare, J. A., Perchoux, C., Pesce, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., MacDonncha, C., Capranica, L., Boccia, S. and Consortium, D. (2017) Behavioral determinants of physical activity across the life course: a “DEterminants of DIet and Physical ACtivity” (DEDIPAC) umbrella systematic literature review International Journal of Behavioral Nutrition and Physical Activity 14 23
  9. Cortis, C., Puggina, A., Pesce, C., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Carlin, A., Simon, C., Ciarapica, D., Condello, G., Coppinger, T., D’Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, A., Ling, F. C. M., Luzak, A., Napolitano, G., Nazare, J. A., O’Donoghue, G., Perchoux, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., Castellani, L., MacDonncha, C., Capranica, L. and Boccia, S. (2017) Psychological determinants of physical activity across the life course: A “DEterminants of DIet and Physical ACtivity” (DEDIPAC) umbrella systematic literature review Plos One 12 25
  10. Disse, E., Ledoux, S., Betry, C., Caussy, C., Maitrepierre, C., Coupaye, M., Laville, M. and Simon, C. (2017) An artificial neural network to predict resting energy expenditure in obesity Clin Nutr
  11. Dupuis, M., Kuczewski, E., Villeneuve, L., Bin-Dorel, S., Haine, M., Falandry, C., Gilbert, T., Passot, G., Glehen, O. and Bonnefoy, M. (2017) Age Nutrition Chirurgie (ANC) study: impact of a geriatric intervention on the screening and management of undernutrition in elderly patients operated on for colon cancer, a stepped wedge controlled trial Bmc Geriatrics 17 9
  12. Garnotel, M., Bastian, T., Romero-Ugalde, H. M., Maire, A., Dugas, J., Zahariev, A., Doron, M., Jallon, P., Charpentier, G., Franc, S., Blanc, S., Bonnet, S. and Simon, C. (2017) Prior automatic posture and activity identification improves physical activity energy expenditure prediction from hip-worn triaxial accelerometry J Appl Physiol (1985) jap.00556.2017
  13. Gilbert, T., Bosquet, A., Thomas-Anterion, C., Bonnefoy, M. and Le Saux, O. (2017) Assessing capacity to consent for research in cognitively impaired older patients Clinical Interventions in Aging 12 1553-1563
  14. Hess, F., Salze, P., Weber, C., Feuillet, T., Charreire, H., Menai, M., Perchoux, C., Nazare, J. A., Simon, C., Oppert, J. M. and Enaux, C. (2017) Active Mobility and Environment: A Pilot Qualitative Study for the Design of a New Questionnaire Plos One 12 15
  15. Lefai, E., Blanc, S., Momken, I., Antoun, E., Chery, I., Zahariev, A., Gabert, L., Bergouignan, A. and Simon, C. (2017) Exercise training improves fat metabolism independent of total energy expenditure in sedentary overweight men, but does not restore lean metabolic phenotype Int J Obes (Lond) 41 1728-1736
  16. Loizides-Mangold, U., Perrin, L., Vandereycken, B., Betts, J. A., Walhin, J. P., Templeman, I., Chanon, S., Weger, B. D., Durand, C., Robert, M., Montoya, J. P., Moniatte, M., Karagounis, L. G., Johnston, J. D., Gachon, F., Lefai, E., Riezman, H. and Dibner, C. (2017) Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro Proceedings of the National Academy of Sciences of the United States of America 114 E8565-E8574
  17. Marchand, L., Decaussin-Petrucci, M., Giraud, S., Cotton, F., Thivolet, C. and Simon, C. (2017) Hibernoma and multiple endocrine neoplasia type 1 syndrome: A non-fortuitous association? A case report and literature review Annales D Endocrinologie 78 194-197
  18. Nguyen, M. F., Bonnefoy, M., Adrait, A., Gueugnon, M., Petitot, C., Collet, L., Roux, A., Perrot, X. and Grp, A. S. (2017) Efficacy of Hearing Aids on the Cognitive Status of Patients with Alzheimer’s Disease and Hearing Loss: A Multicenter Controlled Randomized Trial Journal of Alzheimers Disease 58 123-137
  19. Perchoux, C., Enaux, C., Oppert, J. M., Menai, M., Charreire, H., Salze, P., Weber, C., Hercberg, S., Feuillet, T., Hess, F., Roda, C., Simon, C. and Nazare, J. A. (2017) Individual, Social, and Environmental Correlates of Active Transportation Patterns in French Women Biomed Research International 11
  20. Perchoux, C., Nazare, J. A., Benmarhnia, T., Salze, P., Feuillet, T., Hercberg, S., Hess, F., Menai, M., Weber, C., Charreire, H., Enaux, C., Oppert, J. M. and Simon, C. (2017) Neighborhood educational disparities in active commuting among women: the effect of distance between the place of residence and the place of work/study (an ACTI-Cites study) Bmc Public Health 17 12
  21. Pickering, M. E., Simon, M., Sornay-Rendu, E., Chikh, K., Carlier, M. C., Raby, A. L., Szulc, P. and Confavreux, C. B. (2017) Serum Sclerostin Increases After Acute Physical Activity Calcified Tissue International 101 170-173
  22. Puertas, R. D., Meugnier, E., Romestaing, C., Rey, C., Morel, E., Lachuer, J., Gadot, N., Scridon, A., Julien, C., Tronc, F., Chapuis, B., Valla, C., Janin, A., Pirola, L., Mejat, A., Rome, S. and Chevalier, P. (2017) Atrial fibrillation is associated with hypermethylation in human left atrium, and treatment with decitabine reduces atrial tachyarrhythmias in spontaneously hypertensive rats Translational Research 184 57-67
  23. Romero-Ugalde, H. M., Garnotel, M., Doron, M., Jallon, P., Charpentier, G., Franc, S., Huneker, E., Simon, C. and Bonnet, S. (2017) An original piecewise model for computing energy expenditure from accelerometer and heart rate signals Physiological Measurement 38 1599-161
  24. Ru P, Hu P, Geng F, Mo X, Cheng C, Yoo JY, Cheng X, Wu X, Guo JY, Nakano I, Lefai E, Kaur B, Chakravarti A, Guo D.(2017) Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth.  Cell Rep   18; 1076
  25. Thomas, F., Rome, S., Mery, F., Dawson, E., Montagne, J., Biro, P. A., Beckmann, C., Renaud, F., Poulin, R., Raymond, M. and Ujvari, B. (2017) Changes in diet associated with cancer: An evolutionary perspective Evolutionary Applications 10 651-65

2016

  1. Alexandre J, Ray-Coquard I, Selle F, Floquet A, Cottu P, Weber B, Falandry C, Lebrun D, Pujade-Lauraine E; GINECO-Group.. Clinical presentation and sensitivity to platinum-based chemotherapy (CT) of mucinous advanced epithelial ovarian carcinoma (M-AEOC): The GINECO-Group experience. J Clin Oncol. 2009 May 20;27(15_suppl):5572.
  1. Balcerczyk, A., Rybaczek, D., Wojtala, M., Pirola, L., Okabe, J. and El-Osta, A. (2016) Pharmacological inhibition of arginine and lysine methyltransferases induces nuclear abnormalities and suppresses angiogenesis in human endothelial cells Biochemical Pharmacology 121 18-32
  1. Betry, C., Disse, E., Chambrier, C., Barnoud, D., Gelas, P., Baubet, S., Laville, M., Pelascini, E. and Robert, M. (2016) Need for Intensive Nutrition Care After Bariatric Surgery: Is Mini Gastric Bypass at Fault? JPEN J Parenter Enteral Nutr doi:10.1177/0148607116637935
  1. Bischoff, S. C., Boirie, Y., Cederholm, T., Chourdakis, M., Cuerda, C., Delzenne, N. M., Deutz, N. E., Fouque, D., Genton, L., Gil, C., Koletzko, B., Leon-Sanz, M., Shamir, R., Singer, J., Singer, P., Stroebele-Benschop, N., Thorell, A., Weimann, A. and Barazzoni, R. (2016) Towards a multidisciplinary approach to understand and manage obesity and related diseases Clinical Nutrition doi: 10.1016/j.clnu.2016.11.007
  1. Borges, N. A., Barros, A. F., Nakao, L. S., Dolenga, C. J., Fouque, D. and Mafra, D. (2016) Protein-Bound Uremic Toxins from Gut Microbiota and Inflammatory Markers in Chronic Kidney Disease Journal of Renal Nutrition 26 396-400
  1. Capel, F., Cheraiti, N., Acquaviva, C., Henique, C., Bertrand-Michel, J., Vianey-Saban, C., Prip-Buus, C. and Morio, B. (2016) Oleate dose-dependently regulates palmitate metabolism and insulin signaling in C2C12 myotubes Biochimica et Biophysica Acta 1861 2000-2010
  1. Casteras, S., Abdul-Wahed, A., Soty, M., Vulin, F., Guillou, H., Campana, M., Le Stunff, H., Pirola, L., Rajas, F., Mithieux, G. and Gautier-Stein, A. (2016) The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice Diabetologia 59 2645-2653
  1. Charpiat, B., Derfoufi, S., Larger, M., Janoly-Dumenil, A., Mouchoux, C., Allenet, B., Tod, M., Grassin, J., Boulieu, R., Catala, O., Bedouch, P., Goudable, J. and Vinciguerra, C. (2016) Identification of knowledge deficits of pharmacy students at the beginning of the fifth year of pharmacy practice experience: Proposals to change the content of academic programs Annales Pharmaceutiques Francaises 74 404-12
  1. Chauveau, P., Moreau, K., Lasseur, C., Fouque, D., Combe, C. and Aparicio, M. (2016) Sarcopenia or uremic myopathy in CKD patients Néphrologie & Thérapeutique 12 71-5
  1. Chastin SF, De Craemer M, Lien N, Bernaards C, Buck C, Oppert JM, Nazare JA, Lakerveld J, O’Donoghue G, Holdsworth M, Owen N, Brug J, Cardon G; DEDIPAC consortium, expert working group and consensus panel.. The SOS-framework (Systems of Sedentary behaviours): an international transdisciplinary consensus framework for the study of determinants, research priorities and policy on sedentary behaviour across the life course: a DEDIPAC-study. Int J Behav Nutr Phys Act. 2016 Jul 15;13:83.
  1. Chehimi, M., Robert, M., Bechwaty, M. E., Vial, G., Rieusset, J., Vidal, H., Pirola, L. and Eljaafari, A. (2016) Adipocytes, like their progenitors, contribute to inflammation of adipose tissues through promotion of Th-17 cells and activation of monocytes, in obese subjects Adipocyte 5 275-82
  1. Chriett, S., Le Huerou-Luron, I., Vidal, H. and Pirola, L. (2016) Dysregulation of sirtuins and key metabolic genes in skeletal muscle of pigs with spontaneous intrauterine growth restriction is associated with alterations of circulating IGF-1 General and Comparative Endocrinology 232 76-85
  1. Coffin, B., Maunoury, V., Pattou, F., Hebuterne, X., Schneider, S., Coupaye, M., Ledoux, S., Iglicki, F., Mion, F., Robert, M., Disse, E., Escourrou, J., Tuyeras, G., Le Roux, Y., Arvieux, C., Pouderoux, P., Huten, N., Alfaiate, T., Hajage, D. and Msika, S. (2016) Impact of Intragastric Balloon Before Laparoscopic Gastric Bypass on Patients with Super Obesity: a Randomized Multicenter Study Obesity Surgery doi: 10.1007/s11695-016-2383-x
  1. Condello G, Ling FC, Bianco A, Chastin S, Cardon G, Ciarapica D, Conte D, Cortis C, De Craemer M, Di Blasio A, Gjaka M, Hansen S, Holdsworth M, Iacoviello L, Izzicupo P, Jaeschke L, Leone L, Manoni L, Menescardi C, Migliaccio S, Nazare JA, Perchoux C, Pesce C, Pierik F, Pischon T, Polito A, Puggina A, Sannella A, Schlicht W, Schulz H, Simon C, Steinbrecher A, MacDonncha C, Capranica L; DEDIPAC consortium.. Using concept mapping in the development of the EU-PAD framework (EUropean-Physical Activity Determinants across the life course): a DEDIPAC-study. BMC Public Health. 2016 Nov 9;16(1):1145.
  1. Confavreux, C. B., Casey, R., Varennes, A., Goudable, J., Chapurlat, R. D. and Szulc, P. (2016) Has sclerostin a true endocrine metabolic action complementary to osteocalcin in older men? Osteoporosis International 27 2301-9
  1. Courand, P. Y., Lesiuk, C., Milon, H., Defforges, A., Fouque, D., Harbaoui, B. and Lantelme, P. (2016) Association Between Protein Intake and Mortality in Hypertensive Patients Without Chronic Kidney Disease in the OLD-HTA Cohort Hypertension 67 1142-9
  1. Cuerq, C., Restier, L., Drai, J., Blond, E., Roux, A., Charriere, S., Michalski, M. C., Di Filippo, M., Levy, E., Lachaux, A. and Peretti, N. (2016) Establishment of reference values of alpha-tocopherol in plasma, red blood cells and adipose tissue in healthy children to improve the management of chylomicron retention disease, a rare genetic hypocholesterolemia Orphanet Journal of Rare Diseases 11 114
  1. Dalko E, Tchitchek N, Pays L, Herbert F, Cazenave PA, Ravindran B, Sharma S, Nataf S, Das B, Pied S. Erythropoietin Levels Increase during Cerebral Malaria and Correlate with Heme, Interleukin-10 and Tumor Necrosis Factor-Alpha in India. PLoS One. 2016 Jul 21;11(7):e0158420.
  1. de Brito Alves, J. L., de Oliveira, J. M., Ferreira, D. J., Barros, M. A., Nogueira, V. O., Alves, D. S., Vidal, H., Leandro, C. G., Lagranha, C. J., Pirola, L. and da Costa-Silva, J. H. (2016) Maternal protein restriction induced-hypertension is associated to oxidative disruption at transcriptional and functional levels in the medulla oblongata Clinical and Experimental Pharmacology and Physiology 43 1177-1184
  1. de Brito Alves, J. L., de Sousa, V. P., Cavalcanti Neto, M. P., Magnani, M., Braga, V. A., da Costa-Silva, J. H., Leandro, C. G., Vidal, H. and Pirola, L. (2016) New Insights on the Use of Dietary Polyphenols or Probiotics for the Management of Arterial Hypertension Frontiers in Physiology 7 448
  1. Devaux S, Cizkova D, Quanico J, Franck J, Nataf S, Pays L, Hauberg-Lotte L, Maass P, Kobarg JH, Kobeissy F, Mériaux C, Wisztorski M, Slovinska L, Blasko J, Cigankova V, Fournier I, Salzet M. Proteomic Analysis of the Spatio-temporal Based Molecular Kinetics of Acute Spinal Cord Injury Identifies a Time- and Segment-specific Window for Effective Tissue Repair. Mol Cell Proteomics. 2016 Aug;15(8):2641-70
  1. Di Cataldo, V., Geloen, A., Langlois, J. B., Chauveau, F., Theze, B., Hubert, V., Wiart, M., Chirico, E. N., Rieusset, J., Vidal, H., Pialoux, V. and Canet-Soulas, E. (2016) Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE-/- Mice Frontiers in Physiology 7 453
  1. Disse, E., Pasquer, A., Pelascini, E., Valette, P. J., Betry, C., Laville, M., Gouillat, C. and Robert, M. (2016) Dilatation of Sleeve Gastrectomy: Myth or Reality? Obesity Surgery doi: 10.1007/s11695-016-2261-6
  1. Egli, L., Lecoultre, V., Cros, J., Rosset, R., Marques, A. S., Schneiter, P., Hodson, L., Gabert, L., Laville, M. and Tappy, L. (2016) Exercise performed immediately after fructose ingestion enhances fructose oxidation and suppresses fructose storage The American Journal of Clinical Nutrition 103 348-55
  1. Elisha, B., Disse, E., Chabot, K., Taleb, N., Prud’homme, D., Bernard, S., Rabasa-Lhoret, R. and Bastard, J. P. (2016) Relative contribution of muscle and liver insulin resistance to dysglycemia in postmenopausal overweight and obese women: A MONET group study Annales d’ Endocrinologie (Paris) doi: 10.1016/j.ando.2016.10.00
  1. Farage, N. E., Stockler-Pinto, M. B., Leal, V. O., Cardozo, L. L., Carraro-Eduardo, J. C., Fouque, D. and Mafra, D. (2016) NF-kappaB expression and its association with nutritional status in hemodialysis patients International Urology and Nephrology 48 2089-2094
  1. Fossard, G., Blond, E., Balsat, M., Morisset, S., Giraudier, S., Escoffre-Barbe, M., Labussiere-Wallet, H., Heiblig, M., Bert, A., Etienne, M., Drai, J., Sobh, M., Redonnet-Vernhet, I., Lega, J. C., Mahon, F. X., Etienne, G. and Nicolini, F. E. (2016) Hyperhomocysteinemia and high doses of nilotinib favor cardiovascular events in chronic phase Chronic Myelogenous Leukemia patients Haematologica 101 e86-90
  1. Fouque, D., Chen, J., Chen, W., Garneata, L., Hwang, S. J., Kalantar-Zadeh, K., Kopple, J. D., Mitch, W. E., Piccoli, G., Teplan, V. and Chauveau, P. (2016) Adherence to ketoacids/essential amino acids-supplemented low protein diets and new indications for patients with chronic kidney disease BMC Nephrology 17 63
  1. Frin, A. C., Filippi, J., Boschetti, G., Flourie, B., Drai, J., Ferrari, P., Hebuterne, X. and Nancey, S. (2016) Accuracies of fecal calprotectin, lactoferrin, M2-pyruvate kinase, neopterin and zonulin to predict the response to infliximab in ulcerative colitis Digestive and Liver Disease doi.org/10.1016/j.dld.2016.09.001
  1. Garattini, S., Jakobsen, J. C., Wetterslev, J., Bertele, V., Banzi, R., Rath, A., Neugebauer, E. A., Laville, M., Masson, Y., Hivert, V., Eikermann, M., Aydin, B., Ngwabyt, S., Martinho, C., Gerardi, C., Szmigielski, C. A., Demotes-Mainard, J. and Gluud, C. (2016) Evidence-based clinical practice: Overview of threats to the validity of evidence and how to minimise them European Journal of Internal Medicine 32 13-21
  1. Gastebois, C., Villars, C., Drai, J., Canet-Soulas, E., Blanc, S., Bergouignan, A., Lefai, E. and Simon, C. (2016) Effects of training and detraining on adiponectin plasma concentration and muscle sensitivity in lean and overweight men European Journal of Applied Physiology 116 2135-2144
  1. Geloen, A. and Quintin, L. (2016) Reverse Physiology, i.e., Cellular Versus Integrative Versus Comparative Physiology? alpha-2 Agonists and Septic Shock Critical Care Medicine 44 e238-9
  1. Hachem, M., Geloen, A., Van, A. L., Foumaux, B., Fenart, L., Gosselet, F., Da Silva, P., Breton, G., Lagarde, M., Picq, M. and Bernoud-Hubac, N. (2016) Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid Molecular Neurobiology 53 3205-15
  1. Hage, V., Pelletier, S. and Fouque, D. (2016) No apparent link between serum Klotho and phosphate in human chronic kidney disease Kidney International 89 1399-400
  1. Hannedouche, T., Roth, H., Krummel, T., London, G. M., Jean, G., Bouchet, J. L., Drueke, T. B. and Fouque, D. (2016) Multiphasic effects of blood pressure on survival in hemodialysis patients Kidney International 90 674-84
  1. Jalabert, A., Vial, G., Guay, C., Wiklander, O. P., Nordin, J. Z., Aswad, H., Forterre, A., Meugnier, E., Pesenti, S., Regazzi, R., Danty-Berger, E., Ducreux, S., Vidal, H., El-Andaloussi, S., Rieusset, J. and Rome, S. (2016) Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice Diabetologia 59 1049-58
  1. Junien, C., Panchenko, P., Fneich, S., Pirola, L., Chriett, S., Amarger, V., Kaeffer, B., Parnet, P., Torrisani, J., Bolanos Jimenez, F., Jammes, H. and Gabory, A. (2016) Epigenetics in transgenerational responses to environmental impacts : from facts and gaps Médecine Sciences 32 35-44
  1. Junien, C., Panchenko, P., Pirola, L., Amarger, V., Kaeffer, B., Parnet, P., Torrisani, J., Bolanos Jimenez, F., Jammes, H. and Gabory, A. (2016) The new paradigm of the developmental origin of health and diseases (DOHaD) – Epigenetics and environment: evidence and missing links Médecine Sciences 32 27-34
  1. Kervella, D., Lemoine, S., Sens, F., Dubourg, L., Sebbag, L., Guebre-Egziabher, F., Bonnefoy, E. and Juillard, L. (2016) Cystatin C Versus Creatinine for GFR Estimation in CKD Due to Heart Failure American Journal of Kidney Diseases doi: 10.1053/j.ajkd.2016.09.016
  1. Laforest, S., Michaud, A., Paris, G., Pelletier, M., Vidal, H., Geloen, A. and Tchernof, A. (2016) Comparative analysis of three human adipocyte size measurement methods and their relevance for cardiometabolic risk Obesity (Silver Spring) doi: 10.1002/oby.21697
  1. Le Magueresse-Battistoni, B., Vidal, H. and Naville, D. (2016) Impact of in utero exposure to pollutants on metabolic health in adults Médecine Sciences 32 51-6
  1. Lecomte, M., Couedelo, L., Meugnier, E., Plaisancie, P., Letisse, M., Benoit, B., Gabert, L., Penhoat, A., Durand, A., Pineau, G., Joffre, F., Geloen, A., Vaysse, C., Laugerette, F. and Michalski, M. C. (2016) Dietary emulsifiers from milk and soybean differently impact adiposity and inflammation in association with modulation of colonic goblet cells in high-fat fed mice Molecular Nutrition & Food Research 60 609-20
  1. Le Saux O, Falandry C, Gan HK, You B, Freyer G, Péron J. Inclusion of elderly patients in oncology clinical trials. Ann Oncol. 2016 Sep;27(9):1799-804
  1. Liminet, C., Vouillarmet, J., Chikh, K. and Disse, E. (2016) Antibody-Mediated Insulin Resistance: When Insulin and Insulin Receptor Act as Autoantigens in Humans Canadian Journal of Diabetes 40 462-465
  1. Lips, L., de Roij van Zuijdewijn, C. L., Ter Wee, P. M., Bots, M. L., Blankestijn, P. J., van den Dorpel, M. A., Fouque, D., de Jongh, R., Pelletier, S., Vervloet, M. G., Nube, M. J. and Grooteman, M. P. (2016) Serum sclerostin: relation with mortality and impact of hemodiafiltration Nephrology Dialysis Transplantation doi:10.1093/ndt/gfw246
  1. Makino, A., Hullin-Matsuda, F., Murate, M., Abe, M., Tomishige, N., Fukuda, M., Yamashita, S., Fujimoto, T., Vidal, H., Lagarde, M., Delton, I. and Kobayashi, T. (2016) Acute accumulation of free cholesterol induces the degradation of perilipin 2 and Rab18-dependent fusion of ER and lipid droplets in cultured human hepatocytes Molecular Biology of the Cell 27 3293-3304
  1. Marinho, S. M., Mafra, D., Pelletier, S., Hage, V., Teuma, C., Laville, M., Carraro Eduardo, J. C. and Fouque, D. (2016) In Hemodialysis Patients, Intradialytic Resistance Exercise Improves Osteoblast Function: A Pilot Study Journal of Renal Nutrition 26 341-5
  1. Martinez-Martinez, E., Calvier, L., Rossignol, P., Rousseau, E., Fernandez-Celis, A., Jurado-Lopez, R., Laville, M., Cachofeiro, V. and Lopez-Andres, N. (2016) Galectin-3 inhibition prevents adipose tissue remodelling in obesity International Journal of Obesity 40 1034-8
  1. Mastino, D., Robert, M., Betry, C., Laville, M., Gouillat, C. and Disse, E. (2016) Bariatric Surgery Outcomes in Sarcopenic Obesity Obesity Surgery 26 2355-62
  1. Mensah K, Maire A, Oppert JM, Dugas J, Charreire H, Weber C, Simon C, Nazare JA; ACTI-Cités consortium.. Assessment of sedentary behaviors and transport-related activities by questionnaire: a validation study. BMC Public Health. 2016 Aug 9;16:753.
  1. Merle, E., Roth, H., London, G. M., Jean, G., Hannedouche, T., Bouchet, J. L., Drueke, T., Fouque, D., Daugas, E., French, C. and Phosphate, O. (2016) Low parathyroid hormone status induced by high dialysate calcium is an independent risk factor for cardiovascular death in hemodialysis patients Kidney International 89 666-74
  1. Michaud, A., Laforest, S., Pelletier, M., Nadeau, M., Simard, S., Daris, M., Leboeuf, M., Vidal, H., Geloen, A. and Tchernof, A. (2016) Abdominal adipocyte populations in women with visceral obesity Euroean Journal of Endocrinology 174 227-39
  1. Mirabel-Chambaud, E., N’Guyen, M., Valdeyron, M. L., Quessada, T., Goudable, J., Loras-Duclaux, I., Marotte, S., Heissat, S., Restier, L., Lachaux, A. and Peretti, N. (2016) Dramatic increase of central venous catheter-related infections associated with a high turnover of the nursing team Clinical Nutrition 35 446-52
  1. Nataf S. Clonal selection versus clonal cooperation: the integrated perception of immune objects. F1000Res. 2016 Sep 5;5:2226.
  1. O’Donoghue, G., Perchoux, C., Mensah, K., Lakerveld, J., van der Ploeg, H., Bernaards, C., Chastin, S. F., Simon, C., O’Gorman, D., Nazare, J. A. and consortium, D. (2016) A systematic review of correlates of sedentary behaviour in adults aged 18-65 years: a socio-ecological approach BMC Public Health 16 163
  1. Papastathi, C., Disse, E., Berthiller, J., Laville, M., Gouillat, C. and Robert, M. (2016) Impact of Pregnancy on Weight Loss and Quality of Life Following Gastric Banding Obesity Surgery 26 1843-50
  1. Pasian, C., Azar, R. and Fouque, D. (2016) [Wasting in chronic kidney disease: Refeeding techniques and artificial nutrition practices] Néphrologie & Thérapeutique 12 496-502
  1. Pelascini, E., Disse, E., Pasquer, A., Poncet, G., Gouillat, C. and Robert, M. (2016) Should we wait for metabolic complications before operating on obese patients? Gastric bypass outcomes in metabolically healthy obese individuals Surgery for Obesity and Related Diseases 12 49-56
  1. Pelletier, S., Roth, H., Bouchet, J. L., Drueke, T. B., Hannedouche, T., Jean, G., London, G. and Fouque, D. (2016) Changes in mineral and bone disorder management in a French cohort of hemodialysis patients between 2008 and 2012: The National Bone and Mineral Metabolism observatory (Photo-Graphe 2 and 3) Néphrologie & Thérapeutique 12 171-7
  1. Pippias, M., Jager, K. J., Kramer, A., Leivestad, T., Sanchez, M. B., Caskey, F. J., Collart, F., Couchoud, C., Dekker, F. W., Finne, P., Fouque, D., Heaf, J. G., Hemmelder, M. H., Kramar, R., De Meester, J., Noordzij, M., Palsson, R., Pascual, J., Zurriaga, O., Wanner, C. and Stel, V. S. (2016) The changing trends and outcomes in renal replacement therapy: data from the ERA-EDTA Registry Nephrology Dialysis Transplantation 31 831-41
  1. Rieusset, J., Fauconnier, J., Paillard, M., Belaidi, E., Tubbs, E., Chauvin, M. A., Durand, A., Bravard, A., Teixeira, G., Bartosch, B., Michelet, M., Theurey, P., Vial, G., Demion, M., Blond, E., Zoulim, F., Gomez, L., Vidal, H., Lacampagne, A. and Ovize, M. (2016) Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance Diabetologia 59 614-23
  1. Robert, M., Pasquer, A., Pelascini, E., Valette, P. J., Gouillat, C. and Disse, E. (2016) Impact of sleeve gastrectomy volumes on weight loss results: a prospective study Surgery for Obesity Related Diseases 12 1286-1291
  1. Rodrigues MJ, Zapardiel I, Frélaut M, Brain E, Falandry C. A call for specific geriatric data on cervical cancers. Future Oncol. 2016 May;12(9):1101-4.
  1. Saldanha, J. F., Yi, D., Stockler-Pinto, M. B., Soula, H. A., Chambert, S., Fouque, D., Mafra, D. and Soulage, C. O. (2016) Determination of the binding properties of the uremic toxin phenylacetic acid to human serum albumin Biochimie 125 53-8
  1. Schwarzer, M., Makki, K., Storelli, G., Machuca-Gayet, I., Srutkova, D., Hermanova, P., Martino, M. E., Balmand, S., Hudcovic, T., Heddi, A., Rieusset, J., Kozakova, H., Vidal, H. and Leulier, F. (2016) Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition Science 351 854-7
  1. Seyssel, K., Allirot, X., Nazare, J. A., Roth, H., Blond, E., Charrie, A., Mialon, A., Drai, J., Laville, M. and Disse, E. (2016) Plasma acyl-ghrelin increases after meal initiation: a new insight European Journal of Clinical Nutrition 70 790-4
  1. Seyssel, K., Meugnier, E., Le, K. A., Durand, C., Disse, E., Blond, E., Pays, L., Nataf, S., Brozek, J., Vidal, H., Tappy, L. and Laville, M. (2016) Fructose overfeeding in first-degree relatives of type 2 diabetic patients impacts energy metabolism and mitochondrial functions in skeletal muscle Molecular Nutrition & Food Research 60 2691-2699
  1. Souberbielle, J. C., Deschenes, G., Fouque, D., Groussin, L., Guggenbuhl, P., Jean, G., Linglart, A. and Thomas, T. (2016) Recommendations for the measurement of blood 25-OH vitamin D Annales de Biologie Cliniques (Paris) 74 7-19
  1. Stengel, B., Combe, C., Jacquelinet, C., Briancon, S., Fouque, D., Laville, M., Frimat, L., Pascal, C., Herpe, Y. E., Morel, P., Deleuze, J. F., Schanstra, J. P., Pisoni, R. L., Robinson, B. M. and Massy, Z. A. (2016) [The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study: To better understand chronic kidney disease] Néphrologie & Thérapeutique 12 Suppl 1 S49-56
  1. Stockler-Pinto, M. B., Saldanha, J. F., Yi, D., Mafra, D., Fouque, D. and Soulage, C. O. (2016) The uremic toxin indoxyl sulfate exacerbates reactive oxygen species production and inflammation in 3T3-L1 adipose cells Free Radical Research 50 337-44
  1. Surowska, A., De Giorgi, S., Theytaz, F., Campos, V., Hodson, L., Stefanoni, N., Rey, V., Schneiter, P., Laville, M., Giusti, V., Gabert, L. and Tappy, L. (2016) Effects of roux-en-Y gastric bypass surgery on postprandial fructose metabolism Obesity (Silver Spring) 24 589-96
  1. Szulc, P., Amri, E. Z., Varennes, A., Panaia-Ferrari, P., Fontas, E., Goudable, J., Chapurlat, R. and Breuil, V. (2016) High serum oxytocin is associated with metabolic syndrome in older men – The MINOS study Diabetes Research and Clinical Practice 122 17-27
  1. Teuma, C., Perier-Muzet, M., Pelletier, S., Nouvier, M., Amini-Adl, M., Dijoud, F., Duru, G., Thomas, L., Fouque, D., Laville, M. and Dalle, S. (2016) New insights into renal toxicity of the B-RAF inhibitor, vemurafenib, in patients with metastatic melanoma Cancer Chemotherapy and Pharmacology 78 419-26
  1. Theurey, P., Tubbs, E., Vial, G., Jacquemetton, J., Bendridi, N., Chauvin, M. A., Alam, M. R., Le Romancer, M., Vidal, H. and Rieusset, J. (2016) Mitochondria-associated endoplasmic reticulum membranes allow adaptation of mitochondrial metabolism to glucose availability in the liver Journal of Molecular Cell Biology 8 129-43
  1. Tinquaut F, Freyer G, Chauvin F, Gane N, Pujade-Lauraine E, Falandry C. Prognostic factors for overall survival in elderly patients with advanced ovarian cancer treated with chemotherapy: Results of a pooled analysis of three GINECO phase II trials. Gynecol Oncol. 2016 Oct;143(1):22-6
  1. Vanholder, R., Fouque, D., Glorieux, G., Heine, G. H., Kanbay, M., Mallamaci, F., Massy, Z. A., Ortiz, A., Rossignol, P., Wiecek, A., Zoccali, C., London, G. M., European Renal Association European, D., Transplant Association European, R. and Cardiovascular Medicine working, g. (2016) Clinical management of the uraemic syndrome in chronic kidney disease Lancet Diabetes Endocrinology 4 360-73
  1. Vervloet, M. G., Sezer, S., Massy, Z. A., Johansson, L., Cozzolino, M. and Fouque, D. (2016) The role of phosphate in kidney disease Nature Reviews Nephrology 2017 13:27-38
  1. Viel, S., Besson, L., Charrier, E., Marcais, A., Disse, E., Bienvenu, J., Walzer, T. and Dumontet, C. (2016) Alteration of Natural Killer cell phenotype and function in obese individuals Clinical Immunology doi:10.1016/j.clim.2016.01.007
  1. Villain, C., Fouque, D., Genet, L., Jean, G., Kuentz, F., Lataillade, D., Legrand, E., Moreau-Gaudry, X. and Ecochard, R. (2016) Prognostic Value of Serum Albumin Changes Over Time in Elderly Adults Undergoing Hemodialysis Journal of the American Geriatrics Society 64 1353-4
  1. Vinoy, S., Laville, M. and Feskens, E. J. (2016) Slow-release carbohydrates: growing evidence on metabolic responses and public health interest. Summary of the symposium held at the 12th European Nutrition Conference (FENS 2015) Food Nutrition Research 60 31662
  1. Vouillarmet, J. and Laville, M. (2016) A Case of Familial Partial Lipodystrophy: From Clinical Phenotype to Genetics Canadian Journal of Diabetes 40 376-37
  1. Wojtala, M., Pirola, L. and Balcerczyk, A. (2016) Modulation of the vascular endothelium functioning by dietary components, the role of epigenetics Biofactors doi: 10.1002/biof.1306

2015

1. Bastard, J. P., Rabasa-Lhoret, R., Laville, M., and Disse, E. (2015) Surrogate measures of insulin sensitivity vs the hyperinsulinaemic-euglycaemic clamp: a meta-analysis. Are there not some surrogate indexes lost in this story? Diabetologia. 58, 414-415

2. Benoit, B., Laugerette, F., Plaisancie, P., Geloen, A., Bodennec, J., Estienne, M., Pineau, G., Bernalier-Donadille, A., Vidal, H., and Michalski, M. C. (2015) Increasing fat content from 20 to 45 wt% in a complex diet induces lower endotoxemia in parallel with an increased number of intestinal goblet cells in mice. Nutrition Research. 35, 346-356

3. Berger, E., Heraud, S., Mojallal, A., Lequeux, C., Weiss-Gayet, M., Damour, O., and Geloen, A. (2015) Pathways commonly dysregulated in mouse and human obese adipose tissue: FAT/CD36 modulates differentiation and lipogenesis. Adipocyte. 4, 161-180

4. Berger, E., Vega, N., Weiss-Gayet, M., and Geloen, A. (2015) Gene Network Analysis of Glucose Linked Signaling Pathways and Their Role in Human Hepatocellular Carcinoma Cell Growth and Survival in HuH7 and HepG2 Cell Lines. BioMed Research International. 2015, 821761

5. Betry, C., Challan-Belval, M. A., Bernard, A., Charrie, A., Drai, J., Laville, M., Thivolet, C., and Disse, E. (2015) Increased TSH in obesity: Evidence for a BMI-independent association with leptin. Diabetes & Metabolism. 41, 248-251

6. Blond, E., Goudable, J., and Laville, M. (2015) Nonalcoholic Fatty liver disease and hyperuricemia: a close relation with hepatic insulin resistance after nicotinic Acid treatment? Hormone and Metabolic Research. 47, 546-547

7. Boschetti, G., Garnero, P., Moussata, D., Cuerq, C., Preaudat, C., Duclaux-Loras, R., Mialon, A., Drai, J., Flourie, B., and Nancey, S. (2015) Accuracies of serum and fecal S100 proteins (calprotectin and calgranulin C) to predict the response to TNF antagonists in patients with Crohn’s disease. Inflammatory Bowel Diseases. 21, 331-336

8. Boschetti, G., Laidet, M., Moussata, D., Stefanescu, C., Roblin, X., Phelip, G., Cotte, E., Passot, G., Francois, Y., Drai, J., Del Tedesco, E., Bouhnik, Y., Flourie, B., and Nancey, S. (2015) Levels of Fecal Calprotectin Are Associated With the Severity of Postoperative Endoscopic Recurrence in Asymptomatic Patients With Crohn’s Disease. The American Journal of Gastroenterology. 110, 865-872

9. Capel, F., Acquaviva, C., Pitois, E., Laillet, B., Rigaudiere, J. P., Jouve, C., Pouyet, C., Gladine, C., Comte, B., Vianey Saban, C., and Morio, B. (2015) DHA at nutritional doses restores insulin sensitivity in skeletal muscle by preventing lipotoxicity and inflammation. The Journal of Nutritional Biochemistry. 26, 949-959

10. Chevalier, N., Brucker-Davis, F., Lahlou, N., Coquillard, P., Pugeat, M., Pacini, P., Panaia-Ferrari, P., Wagner-Mahler, K., and Fenichel, P. (2015) A negative correlation between insulin-like peptide 3 and bisphenol A in human cord blood suggests an effect of endocrine disruptors on testicular descent during fetal development. Human Reproduction. 30, 447-453

11. Chriett, S., and Pirola, L. (2015) Essential roles of four-carbon backbone chemicals in the control of metabolism. World Journal of Biological Chemistry. 6, 223-230

12. Croze, M. L., Geloen, A., and Soulage, C. O. (2015) Abnormalities in myo-inositol metabolism associated with type 2 diabetes in mice fed a high-fat diet: benefits of a dietary myo-inositol supplementation. The British Journal of Nutrition. 113, 1862-1875

13. Cuerq, C., Peretti, N., Chikh, K., Mialon, A., Guillaumont, M., Drai, J., and Blond, E. (2015) Overview of the in vitro stability of commonly measured vitamins and carotenoids in whole blood. Annals of Clinical Biochemistry. 52, 259-269

14. Eljaafari, A., Robert, M., Chehimi, M., Chanon, S., Durand, C., Vial, G., Bendridi, N., Madec, A. M., Disse, E., Laville, M., Rieusset, J., Lefai, E., Vidal, H., and Pirola, L. (2015) Adipose Tissue-Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocyte Activation. Diabetes. 64, 2477-2488

15. Hachem, M., Geloen, A., Van, A. L., Foumaux, B., Fenart, L., Gosselet, F., Da Silva, P., Breton, G., Lagarde, M., Picq, M., and Bernoud-Hubac, N. (2015) Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid. Molecular neurobiology.
16. Heinrich-Balard, L., Zeinyeh, W., Dechaud, H., Rivory, P., Roux, A., Pugeat, M., and Cohen, R. (2015) Inverse relationship between hSHBG affinity for testosterone and hSHBG concentration revealed by surface plasmon resonance. Molecular and cellular endocrinology. 399, 201-207

17. Honnorat, D., Disse, E., Millot, L., Mathiotte, E., Claret, M., Charrie, A., Drai, J., Garnier, L., Maurice, C., Durand, E., Simon, C., Dupuis, O., and Thivolet, C. (2015) Are third-trimester adipokines associated with higher metabolic risk among women with gestational diabetes? Diabetes & Metabolism. 41, 393-400

18. Huvenne, H., Le Beyec, J., Pepin, D., Alili, R., Kherchiche, P. P., Jeannic, E., Frelut, M. L., Lacorte, J. M., Nicolino, M., Viard, A., Laville, M., Ledoux, S., Tounian, P., Poitou, C., Dubern, B., and Clement, K. (2015) Seven novel deleterious LEPR mutations found in early-onset obesity: a DeltaExon6-8 shared by subjects from Reunion Island, France, suggests a founder effect. The Journal of Clinical Endocrinology and Metabolism. 100, E757-766

19. Koppe, L., Mafra, D., and Fouque, D. (2015) Probiotics and chronic kidney disease. Kidney international. 88, 958-966

20. Le Guen, M., Chate, V., Hininger-Favier, I., Laillet, B., Morio, B., Pieroni, G., Schlattner, U., Pison, C., and Dubouchaud, H. (2016) A 9-wk docosahexaenoic acid-enriched supplementation improves endurance exercise capacity and skeletal muscle mitochondrial function in adult rats. Am J Physiol Endocrinol Metab. 310, E213-224

21. Lecomte, M., Couedelo, L., Meugnier, E., Plaisancie, P., Letisse, M., Benoit, B., Gabert, L., Penhoat, A., Durand, A., Pineau, G., Joffre, F., Geloen, A., Vaysse, C., Laugerette, F., and Michalski, M. C. (2016) Dietary emulsifiers from milk and soybean differently impact adiposity and inflammation in association with modulation of colonic goblet cells in high-fat fed mice. Molecular nutrition & food research. 60, 609-620

22. Mafra, D., and Fouque, D. (2015) Gut microbiota and inflammation in chronic kidney disease patients. Clin Kidney J. 8, 332-334

23. Millon, A., Sigovan, M., Boussel, L., Mathevet, J. L., Louzier, V., Paquet, C., Geloen, A., Provost, N., Majd, Z., Patsouris, D., Serusclat, A., and Canet-Soulas, E. (2015) Low WSS Induces Intimal Thickening, while Large WSS Variation and Inflammation Induce Medial Thinning, in an Animal Model of Atherosclerosis. PLoS One. 10, e0141880

24. Naville, D., Labaronne, E., Vega, N., Pinteur, C., Canet-Soulas, E., Vidal, H., and Le Magueresse-Battistoni, B. (2015) Metabolic outcome of female mice exposed to a mixture of low-dose pollutants in a diet-induced obesity model. PLoS One. 10, e0124015

25. Papastathi, C., Disse, E., Berthiller, J., Laville, M., Gouillat, C., and Robert, M. (2015) Impact of Pregnancy on Weight Loss and Quality of Life Following Gastric Banding. Obesity surgery.
26. Perez, E. C., Elie, J. E., Boucaud, I. C., Crouchet, T., Soulage, C. O., Soula, H. A., Theunissen, F. E., and Vignal, C. (2015) Physiological resonance between mates through calls as possible evidence of empathic processes in songbirds. Hormones and Behavior. 75, 130-141

27. Perrin, L., Loizides-Mangold, U., Skarupelova, S., Pulimeno, P., Chanon, S., Robert, M., Bouzakri, K., Modoux, C., Roux-Lombard, P., Vidal, H., Lefai, E., and Dibner, C. (2015) Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion. Molecular metabolism. 4, 834-845

28. Revel, F., Gilbert, T., Roche, S., Drai, J., Blond, E., Ecochard, R., and Bonnefoy, M. (2015) Influence of oxidative stress biomarkers on cognitive decline. Journal of Alzheimer’s disease. 45, 553-560

29. Rieusset, J., Fauconnier, J., Paillard, M., Belaidi, E., Tubbs, E., Chauvin, M. A., Durand, A., Bravard, A., Teixeira, G., Bartosch, B., Michelet, M., Theurey, P., Vial, G., Demion, M., Blond, E., Zoulim, F., Gomez, L., Vidal, H., Lacampagne, A., and Ovize, M. (2016) Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance. Diabetologia. 59, 614-623

30. Robert, M., Pechoux, A., Marion, D., Laville, M., Gouillat, C., and Disse, E. (2015) Relevance of Roux-en-Y gastric bypass volumetry using 3-dimensional gastric computed tomography with gas to predict weight loss at 1 year. Surgery for obesity and related diseases. 11, 26-31

31. Rossignol, P., Massy, Z. A., Azizi, M., Bakris, G., Ritz, E., Covic, A., Goldsmith, D., Heine, G. H., Jager, K. J., Kanbay, M., Mallamaci, F., Ortiz, A., Vanholder, R., Wiecek, A., Zoccali, C., London, G. M., Stengel, B., Fouque, D., group, Era-Edta Eureca- m working, Red de Investigacion Renal, network, Cardiovascular, and Renal Clinical Trialists, network (2015) The double challenge of resistant hypertension and chronic kidney disease. Lancet. 386, 1588-1598

32. Salvatore, G., Bernoud-Hubac, N., Bissay, N., Debard, C., Daira, P., Meugnier, E., Proamer, F., Hanau, D., Vidal, H., Arico, M., Delprat, C., and Mahtouk, K. (2015) Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A. Journal of lipid research. 56, 1110-1122

33. Soula, H. A., Geloen, A., and Soulage, C. O. (2015) Model of adipose tissue cellularity dynamics during food restriction. Journal of theoretical biology. 364, 189-196

34. Steiber, A. L., Leon, J. B., Hand, R. K., Murphy, W. J., Fouque, D., Parrott, J. S., Kalantar-Zadeh, K., and Cuppari, L. (2015) Using a web-based nutrition algorithm in hemodialysis patients. Journal of renal nutrition. 25, 6-16

35. Vella, R. E., Pillon, N. J., Zarrouki, B., Croze, M. L., Koppe, L., Guichardant, M., Pesenti, S., Chauvin, M. A., Rieusset, J., Geloen, A., and Soulage, C. O. (2015) Ozone exposure triggers insulin resistance through muscle c-Jun N-terminal kinase activation. Diabetes. 64, 1011-1024

36. Vericel, E., Colas, R., Calzada, C., Le, Q. H., Feugier, N., Cugnet, C., Vidal, H., Laville, M., Moulin, P., and Lagarde, M. (2015) Moderate oral supplementation with docosahexaenoic acid improves platelet function and oxidative stress in type 2 diabetic patients. Thrombosis and haemostasis. 114, 289-296

37. Vial, G., Chauvin, M. A., Bendridi, N., Durand, A., Meugnier, E., Madec, A. M., Bernoud-Hubac, N., Pais de Barros, J. P., Fontaine, E., Acquaviva, C., Hallakou-Bozec, S., Bolze, S., Vidal, H., and Rieusset, J. (2015) Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice model. Diabetes. 64, 2254-2264

38. Villain, C., Ecochard, R., Genet, L., Jean, G., Kuentz, F., Lataillade, D., Legrand, E., Moreau-Gaudry, X., and Fouque, D. (2015) Impact of BMI Variations on Survival in Elderly Hemodialysis Patients. Journal of renal nutrition. 25, 488-493

39. Vogelzang, J. L., van Stralen, K. J., Noordzij, M., Diez, J. A., Carrero, J. J., Couchoud, C., Dekker, F. W., Finne, P., Fouque, D., Heaf, J. G., Hoitsma, A., Leivestad, T., de Meester, J., Metcalfe, W., Palsson, R., Postorino, M., Ravani, P., Vanholder, R., Wallner, M., Wanner, C., Groothoff, J. W., and Jager, K. J. (2015) Mortality from infections and malignancies in patients treated with renal replacement therapy: data from the ERA-EDTA registry. Nephrology, dialysis, transplantation. 30, 1028-1037

40. Vors, C., Drai, J., Gabert, L., Pineau, G., Laville, M., Vidal, H., Guichard, E., Michalski, M. C., and Feron, G. (2015) Salivary composition in obese vs normal-weight subjects: towards a role in postprandial lipid metabolism? International Journal of Obesity. 39, 1425-1428

41. Vors, C., Pineau, G., Drai, J., Meugnier, E., Pesenti, S., Laville, M., Laugerette, F., Malpuech-Brugere, C., Vidal, H., and Michalski, M. C. (2015) Postprandial Endotoxemia Linked With Chylomicrons and Lipopolysaccharides Handling in Obese Versus Lean Men: A Lipid Dose-Effect Trial. The Journal of Clinical Endocrinology and Metabolism. 100, 3427-3435

2014

1. Allirot, X., Seyssel, K., Saulais, L., Roth, H., Charrie, A., Drai, J., Goudable, J., Blond, E., Disse, E., and Laville, M. (2014) Effects of a breakfast spread out over time on the food intake at lunch and the hormonal responses in obese men. Physiology & behavior. 127, 37-44

2. Bacchetta, J., Pelletier, S., Jean, G., and Fouque, D. (2014) Immune, metabolic and epidemiological aspects of vitamin D in chronic kidney disease and transplant patients. Clinical biochemistry.

3. Benoit, B., Plaisancie, P., Geloen, A., Estienne, M., Debard, C., Meugnier, E., Loizon, E., Daira, P., Bodennec, J., Cousin, O., Vidal, H., Laugerette, F., and Michalski, M. C. (2014) Pasture v. standard dairy cream in high-fat diet-fed mice: improved metabolic outcomes and stronger intestinal barrier. The British journal of nutrition. 1-16

4. Bessa, B., de Oliveira Leal, V., Moraes, C., Barboza, J., Fouque, D., and Mafra, D. (2014) Resistance Training in Hemodialysis Patients: A Review. Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses.

5. Blanc, S., Ruggiero, F., Birot, A. M., Acloque, H., Decimo, D., Lerat, E., Ohlmann, T., Samarut, J., and Mey, A. (2014) Subcellular localization of ENS-1/ERNI in chick embryonic stem cells. PloS one. 9, e92039

6. Blond, E., Rieusset, J., Alligier, M., Lambert-Porcheron, S., Bendridi, N., Gabert, L., Chetiveaux, M., Debard, C., Chauvin, M. A., Normand, S., Roth, H., de Gouville, A. C., Krempf, M., Vidal, H., Goudable, J., and Laville, M. (2014) Nicotinic Acid effects on insulin sensitivity and hepatic lipid metabolism: an in vivo to in vitro study. Hormone and metabolic research. 46, 390-396

7. Boirie, Y., Morio, B., Caumon, E., and Cano, N. J. (2014) Nutrition and protein energy homeostasis in elderly. Mechanisms of ageing and development. 136-137, 76-84

8. Borges, N., Moraes, C., Barros, A. F., Carraro-Eduardo, J. C., Fouque, D., and Mafra, D. (2014) Acyl-ghrelin and obestatin plasma levels in different stages of chronic kidney disease. Journal of renal nutrition. 24, 100-104

9. Bravard, A., Vial, G., Chauvin, M. A., Rouille, Y., Bailleul, B., Vidal, H., and Rieusset, J. (2014) FTO contributes to hepatic metabolism regulation through regulation of leptin action and STAT3 signalling in liver. Cell communication and signaling : CCS. 12, 4

10. Conway, G. S., Dewailly, D., Diamanti-Kandarakis, E., Escobar Morreale, H., Franks, S., Gambineri, A., Kelestimur, F., Macut, D., Micic, D., Pasquali, R., Pfeifer, M., Pignatelli, D., Pugeat, M., and Yildiz, B. (2014) The Polycystic Ovary Syndrome: an Endocrinological Perspective from the European Society of Endocrinology. European journal of endocrinology / European Federation of Endocrine Societies.

11. Disse, E., Pasquer, A., Espalieu, P., Poncet, G., Gouillat, C., and Robert, M. (2014) Greater Weight Loss with the Omega Loop Bypass Compared to the Roux-en-Y Gastric Bypass: a Comparative Study. Obesity surgery.

12. Eyenga, P., Roussel, D., Morel, J., Rey, B., Romestaing, C., Teulier, L., Sheu, S. S., Goudable, J., Negrier, C., and Viale, J. P. (2014) Early septic shock induces loss of oxidative phosphorylation yield plasticity in liver mitochondria. Journal of physiology and biochemistry. 70, 285-296

13. Fluck, R. J., Fouque, D., and Lockridge, R. S., Jr. (2014) Nephrologists’ perspectives on dialysis treatment: results of an international survey. BMC nephrology. 15, 16

14. Fontas, M., Poulain, J. P., Souquet, P. J., Laville, M., Giboreau, A., Bensafi, M., and Mazieres, J. (2014) [Socio-anthropological perspective of the under nutrition care of cancer patients]. Bulletin du cancer. 101, 258-265

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16. Fouque, D., Cruz Casal, M., Lindley, E., Rogers, S., Pancirova, J., Kernc, J., and Copley, J. B. (2014) Dietary trends and management of hyperphosphatemia among patients with chronic kidney disease: an international survey of renal care professionals. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 24, 110-115

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18. Hage, V., Pelletier, S., Dubourg, L., Drai, J., Cuerq, C., Lemoine, S., Hadj-Aissa, A., Laville, M., Fouque, D., Chinnappa, S., Tan, L. B., Mooney, A., El Nahas, A. M., Glorieux, G., Vanholder, R., White, E., Jankowski, J., Janke, D., Ruth, M., Lemke, H. D., Jankowski, V., Troeger, T., Wessely, M., Bidlingmaier, M., Schonermarck, U., Hadjamu, N., Rau, S., Fischereder, M., Kim, Y., Hong, Y. A., Kim, M. Y., Lim, J. H., Chang, Y. S., and Park, C. W. (2014) Uremic toxicity. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 29 Suppl 3, iii19-iii20

19. Harmel, E., Grenier, E., Bendjoudi Ouadda, A., El Chebly, M., Ziv, E., Beaulieu, J. F., Sane, A., Spahis, S., Laville, M., and Levy, E. (2014) AMPK in the small intestine in normal and pathophysiological conditions. Endocrinology. 155, 873-888

20. Koppe, L., and Fouque, D. (2014) Nutrition: Intradialytic oral nutrition–the ultimate conviction. Nature reviews. Nephrology. 10, 11-12

21. Laugerette, F., Alligier, M., Bastard, J. P., Drai, J., Chanseaume, E., Lambert-Porcheron, S., Laville, M., Morio, B., Vidal, H., and Michalski, M. C. (2014) Overfeeding increases postprandial endotoxemia in men: Inflammatory outcome may depend on LPS transporters LBP and sCD14. Molecular nutrition & food research.

22. Lemoine, S., Guebre-Egziabher, F., Sens, F., Nguyen-Tu, M. S., Juillard, L., Dubourg, L., and Hadj-Aissa, A. (2014) Accuracy of GFR Estimation in Obese Patients. Clinical journal of the American Society of Nephrology : CJASN. 9, 720-727

23. Manfo, F. P., Nantia, E. A., Dechaud, H., Tchana, A. N., Zabot, M. T., Pugeat, M., and Moundipa, P. F. (2014) Protective effect of Basella alba and Carpolobia alba extracts against maneb-induced male infertility. Pharmaceutical biology. 52, 97-104

24. Mourmoura, E., Chate, V., Couturier, K., Laillet, B., Vial, G., Rigaudiere, J. P., Morio, B., Malpuech-Brugere, C., Azarnoush, K., and Demaison, L. (2014) Body adiposity dictates different mechanisms of increased coronary reactivity related to improved in vivo cardiac function. Cardiovascular diabetology. 13, 54

25. Nagler, E. V., Webster, A. C., Bolignano, D., Haller, M. C., Nistor, I., van der Veer, S. N., Fouque, D., and Van Biesen, W. (2014) European Renal Best Practice (ERBP) Guideline development methodology: towards the best possible guidelines. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 29, 731-738

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33. Stockler-Pinto, M. B., Fouque, D., Soulage, C. O., Croze, M., and Mafra, D. (2014) Indoxyl Sulfate and p-Cresyl Sulfate in Chronic Kidney Disease. Could These Toxins Modulate the Antioxidant Nrf2-Keap1 Pathway? Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.

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2013

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3. Allirot, X., Saulais, L., Seyssel, K., Graeppi-Dulac, J., Roth, H., Charrie, A., Drai, J., Goudable, J., Blond, E., Disse, E., and Laville, M. (2013) An isocaloric increase of eating episodes in the morning contributes to decrease energy intake at lunch in lean men. Physiology & behavior. 110-111, 169-178

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40. Haynes, V., Connor, T., Tchernof, A., Vidal, H., and Dubois, S. (2013) Metallothionein 2a gene expression is increased in subcutaneous adipose tissue of type 2 diabetic patients. Molecular genetics and metabolism. 108, 90-94

41. Hokayem, M., Blond, E., Vidal, H., Lambert, K., Meugnier, E., Feillet-Coudray, C., Coudray, C., Pesenti, S., Luyton, C., Lambert-Porcheron, S., Sauvinet, V., Fedou, C., Brun, J. F., Rieusset, J., Bisbal, C., Sultan, A., Mercier, J., Goudable, J., Dupuy, A. M., Cristol, J. P., Laville, M., and Avignon, A. (2013) Grape polyphenols prevent fructose-induced oxidative stress and insulin resistance in first-degree relatives of type 2 diabetic patients. Diabetes care. 36, 1454-1461

42. Ikizler, T. A., Cano, N. J., Franch, H., Fouque, D., Himmelfarb, J., Kalantar-Zadeh, K., Kuhlmann, M. K., Stenvinkel, P., TerWee, P., Teta, D., Wang, A. Y., and Wanner, C. (2013) Prevention and treatment of protein energy wasting in chronic kidney disease patients: a consensus statement by the International Society of Renal Nutrition and Metabolism. Kidney international. 84, 1096-1107

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51. Kumashiro, N., Yoshimura, T., Cantley, J. L., Majumdar, S. K., Guebre-Egziabher, F., Kursawe, R., Vatner, D. F., Fat, I., Kahn, M., Erion, D. M., Zhang, X. M., Zhang, D., Manchem, V. P., Bhanot, S., Gerhard, G. S., Petersen, K. F., Cline, G. W., Samuel, V. T., and Shulman, G. I. (2013) Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats. Hepatology. 57, 1763-1772

52. Lahjibi, E., Heude, B., Dekker, J. M., Hojlund, K., Laville, M., Nolan, J., Oppert, J. M., and Balkau, B. (2013) Impact of objectively measured sedentary behaviour on changes in insulin resistance and secretion over 3 years in the RISC study: interaction with weight gain. Diabetes & metabolism. 39, 217-225

53. Laville, M., Vors, C., Nazare, J. A., and Michalski, M. C. (2013) [Importance of the postprandial phase in human health]. Bulletin de l’Academie nationale de medecine. 197, 65-77; discussion 77-68

54. Le Beyec, J., Cugnet-Anceau, C., Pepin, D., Alili, R., Cotillard, A., Lacorte, J. M., Basdevant, A., Laville, M., and Clement, K. (2013) Homozygous leptin receptor mutation due to uniparental disomy of chromosome 1: response to bariatric surgery. The Journal of clinical endocrinology and metabolism. 98, E397-402

55. Lefils-Lacourtablaise, J., Socorro, M., Geloen, A., Daira, P., Debard, C., Loizon, E., Guichardant, M., Dominguez, Z., Vidal, H., Lagarde, M., and Bernoud-Hubac, N. (2013) The eicosapentaenoic acid metabolite 15-deoxy-delta(12,14)-prostaglandin J3 increases adiponectin secretion by adipocytes partly via a PPARgamma-dependent mechanism. PloS one. 8, e63997

56. Legendre, C. M., Licht, C., Muus, P., Greenbaum, L. A., Babu, S., Bedrosian, C., Bingham, C., Cohen, D. J., Delmas, Y., Douglas, K., Eitner, F., Feldkamp, T., Fouque, D., Furman, R. R., Gaber, O., Herthelius, M., Hourmant, M., Karpman, D., Lebranchu, Y., Mariat, C., Menne, J., Moulin, B., Nurnberger, J., Ogawa, M., Remuzzi, G., Richard, T., Sberro-Soussan, R., Severino, B., Sheerin, N. S., Trivelli, A., Zimmerhackl, L. B., Goodship, T., and Loirat, C. (2013) Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. The New England journal of medicine. 368, 2169-2181

57. Mafra, D., Barros, A. F., and Fouque, D. (2013) Dietary protein metabolism by gut microbiota and its consequences for chronic kidney disease patients. Future microbiology. 8, 1317-1323

58. Moreno-Navarrete, J. M., Escote, X., Ortega, F., Serino, M., Campbell, M., Michalski, M. C., Laville, M., Xifra, G., Luche, E., Domingo, P., Sabater, M., Pardo, G., Waget, A., Salvador, J., Giralt, M., Rodriguez-Hermosa, J. I., Camps, M., Kolditz, C. I., Viguerie, N., Galitzky, J., Decaunes, P., Ricart, W., Fruhbeck, G., Villarroya, F., Mingrone, G., Langin, D., Zorzano, A., Vidal, H., Vendrell, J., Burcelin, R., Vidal-Puig, A., and Fernandez-Real, J. M. (2013) A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction. Diabetologia. 56, 2524-2537

59. Mourmoura, E., Vial, G., Laillet, B., Rigaudiere, J. P., Hininger-Favier, I., Dubouchaud, H., Morio, B., and Demaison, L. (2013) Preserved endothelium-dependent dilatation of the coronary microvasculature at the early phase of diabetes mellitus despite the increased oxidative stress and depressed cardiac mechanical function ex vivo. Cardiovascular diabetology. 12, 49

60. Nancey, S., Boschetti, G., Moussata, D., Cotte, E., Peyras, J., Cuerq, C., Haybrard, J., Charlois, A. L., Mialon, A., Chauvenet, M., Stroeymeyt, K., Kaiserlian, D., Drai, J., and Flourie, B. (2013) Neopterin is a novel reliable fecal marker as accurate as calprotectin for predicting endoscopic disease activity in patients with inflammatory bowel diseases. Inflammatory bowel diseases. 19, 1043-1052

61. Naville, D., Pinteur, C., Vega, N., Menade, Y., Vigier, M., Le Bourdais, A., Labaronne, E., Debard, C., Luquain-Costaz, C., Begeot, M., Vidal, H., and Le Magueresse-Battistoni, B. (2013) Low-dose food contaminants trigger sex-specific, hepatic metabolic changes in the progeny of obese mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 27, 3860-3870

62. Pataky, Z., Golay, A., Laville, M., Disse, E., Mitrakou, A., Guidone, C., Gabriel, R., and Bobbioni-Harsch, E. (2013) Fasting insulin at baseline influences the number of cardiometabolic risk factors and R-R interval at 3years in a healthy population: the RISC Study. Diabetes & metabolism. 39, 330-336

63. Pelletier, C. C., Koppe, L., Croze, M. L., Kalbacher, E., Vella, R. E., Guebre-Egziabher, F., Geloen, A., Badet, L., Fouque, D., and Soulage, C. O. (2013) White adipose tissue overproduces the lipid-mobilizing factor zinc alpha2-glycoprotein in chronic kidney disease. Kidney international. 83, 878-886

64. Pelletier, S., Dubourg, L., Carlier, M. C., Hadj-Aissa, A., and Fouque, D. (2013) The relation between renal function and serum sclerostin in adult patients with CKD. Clinical journal of the American Society of Nephrology : CJASN. 8, 819-823

65. Pina, G., Dubois, S., Murat, A., Berger, N., Niccoli, P., Peix, J. L., Cohen, R., Guillausseau, C., Charrie, A., Chabre, O., Cornu, C., Borson-Chazot, F., and Rohmer, V. (2013) Is basal ultrasensitive measurement of calcitonin capable of substituting for the pentagastrin-stimulation test? Clinical endocrinology. 78, 358-364

66. Robert, M., Ferrand-Gaillard, C., Disse, E., Espalieu, P., Simon, C., Laville, M., Gouillat, C., and Thivolet, C. (2013) Predictive factors of type 2 diabetes remission 1 year after bariatric surgery: impact of surgical techniques. Obesity surgery. 23, 770-775

67. Robert, M., Pelascini, E., Disse, E., Espalieu, P., Poncet, G., Laville, M., and Gouillat, C. (2013) Preoperative fat-free mass: a predictive factor of weight loss after gastric bypass. Obesity surgery. 23, 446-455

68. Rouffet, D., Villars, C., Fissoune, R., Sappey-Marinier, D., Laville, M., Ibarrola, D., Sothier, M., Monnet, M. F., Ovize, M., Bonnefoy, M., Boesch, C., and Canet-Soulas, E. (2013) Intramyocellular lipid variations in active older men: relationship with aerobic fitness. Acta Physiol (Oxf). 207, 516-523

69. Salinari, S., Debard, C., Bertuzzi, A., Durand, C., Zimmet, P., Vidal, H., and Mingrone, G. (2013) Jejunal proteins secreted by db/db mice or insulin-resistant humans impair the insulin signaling and determine insulin resistance. PloS one. 8, e56258

70. Serdiuk, T., Lysenko, V., Mognetti, B., Skryshevsky, V., and Geloen, A. (2013) Impact of cell division on intracellular uptake and nuclear targeting with fluorescent SiC-based nanoparticles. Journal of biophotonics. 6, 291-297

71. Soula, H., Care, B., Beslon, G., and Berry, H. (2013) Anomalous versus slowed-down Brownian diffusion in the ligand-binding equilibrium. Biophysical journal. 105, 2064-2073

72. Soula, H. A., Julienne, H., Soulage, C. O., and Geloen, A. (2013) Modelling adipocytes size distribution. Journal of theoretical biology. 332, 89-95

73. Soulage, C. O., Koppe, L., and Fouque, D. (2013) Protein-bound uremic toxins…new targets to prevent insulin resistance and dysmetabolism in patients with chronic kidney disease. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 23, 464-466

74. Stengel, B., Combe, C., Jacquelinet, C., Briancon, S., Fouque, D., Laville, M., Frimat, L., Pascal, C., Herpe, Y. E., Deleuze, J. F., Schanstra, J., Pisoni, R. L., Robinson, B. M., and Massy, Z. A. (2013) The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association.

75. Thauvin-Robinet, C., Auclair, M., Duplomb, L., Caron-Debarle, M., Avila, M., St-Onge, J., Le Merrer, M., Le Luyer, B., Heron, D., Mathieu-Dramard, M., Bitoun, P., Petit, J. M., Odent, S., Amiel, J., Picot, D., Carmignac, V., Thevenon, J., Callier, P., Laville, M., Reznik, Y., Fagour, C., Nunes, M. L., Capeau, J., Lascols, O., Huet, F., Faivre, L., Vigouroux, C., and Riviere, J. B. (2013) PIK3R1 Mutations Cause Syndromic Insulin Resistance with Lipoatrophy. American journal of human genetics (In press).

76. Thivel, D., Brakonieki, K., Duche, P., Morio, B., Boirie, Y., and Laferrere, B. (2013) Surgical weight loss: impact on energy expenditure. Obesity surgery. 23, 255-266

77. Thivel, D., Duche, P., and Morio, B. (2013) Energy balance in youth: an ‘inter-dynamic’ concept? The British journal of nutrition. 109, 581-582

78. Thivel, D., Metz, L., Aucouturier, J., Brakoniecki, K., Duche, P., and Morio, B. (2013) The effects of imposed sedentary behavior and exercise on energy intake in adolescents with obesity. Journal of developmental and behavioral pediatrics : JDBP. 34, 616-622

79. Tian, S., Mioche, L., Denis, J. B., and Morio, B. (2013) A multivariate model for predicting segmental body composition. The British journal of nutrition. 110, 2260-2270

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81. Vinoy, S., Normand, S., Meynier, A., Sothier, M., Louche-Pelissier, C., Peyrat, J., Maitrepierre, C., Nazare, J. A., Brand-Miller, J., and Laville, M. (2013) Cereal processing influences postprandial glucose metabolism as well as the GI effect. Journal of the American College of Nutrition. 32, 79-91

82. Vors, C., Pineau, G., Gabert, L., Drai, J., Louche-Pelissier, C., Defoort, C., Lairon, D., Desage, M., Danthine, S., Lambert-Porcheron, S., Vidal, H., Laville, M., and Michalski, M. C. (2013) Modulating absorption and postprandial handling of dietary fatty acids by structuring fat in the meal: a randomized crossover clinical trial. The American journal of clinical nutrition. 97, 23-36

83. Zitt, E., Fouque, D., Jacobson, S. H., Malberti, F., Ryba, M., Urena, P., Rix, M., Dehmel, B., Manamley, N., and Vervloet, M. (2013) Serum phosphorus reduction in dialysis patients treated with cinacalcet for secondary hyperparathyroidism results mainly from parathyroid hormone reduction. Clinical kidney journal. 6, 287-294

2012

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2. Allirot, X., Saulais, L., Disse, E., Roth, H., Cazal, C., and Laville, M. (2012) Validation of a buffet meal design in an experimental restaurant. Appetite 58, 889-897

3. Aparicio, M., Bellizzi, V., Chauveau, P., Cupisti, A., Ecder, T., Fouque, D., Garneata, L., Lin, S., Mitch, W. E., Teplan, V., Zakar, G., and Yu, X. (2012) Protein-restricted diets plus keto/amino acids–a valid therapeutic approach for chronic kidney disease patients. J Ren Nutr 22, S1-21

4. Assadi, A., Desebbe, O., Rimmelé, T., Arnal, F., Goudable, J., Chassard, D., and Allaouchiche, B. (2012) Small-volume hypertonic saline/pentastarch improves ileal mucosal microcirculation in experimental peritonitis. In Infectious Disease reports Vol. 4 pp. 73-83

5. Avbelj Stefanija, M., Jeanpierre, M., Sykiotis, G. P., Young, J., Quinton, R., Abreu, A. P., Plummer, L., Au, M. G., Balasubramanian, R., Dwyer, A. A., Florez, J. C., Cheetham, T., Pearce, S. H., Purushothaman, R., Schinzel, A., Pugeat, M., Jacobson-Dickman, E. E., Ten, S., Latronico, A. C., Gusella, J. F., Dode, C., Crowley, W. F., Jr., and Pitteloud, N. (2012) An ancient founder mutation in PROKR2 impairs human reproduction. Hum Mol Genet 21, 4314-4324

6. Avesani, C. M., Trolonge, S., Deleaval, P., Baria, F., Mafra, D., Faxen-Irving, G., Chauveau, P., Teta, D., Kamimura, M. A., Cuppari, L., Chan, M., Heimburger, O., and Fouque, D. (2012) Physical activity and energy expenditure in haemodialysis patients: an international survey. Nephrol Dial Transplant 27, 2430-2434

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42. Prouillac, C., Koraichi, F., Videmann, B., Mazallon, M., Rodriguez, F., Baltas, M., and Lecoeur, S. (2012) In vitro toxicological effects of estrogenic mycotoxins on human placental cells: structure activity relationships. Toxicol Appl Pharmacol 259, 366-375

43. Rieusset, J., Chauvin, M. A., Durand, A., Bravard, A., Laugerette, F., Michalski, M. C., and Vidal, H. (2012) Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance. Biochem Biophys Res Commun 417, 439-445

44. Rieusset, J., Fauconnier, J., Paillard, M., Belaidi, E., Tubbs, E., Chauvin, M. A., Durand, A., Bravard, A., Teixeira, G., Bartosch, B., Michelet, M., Theurey, P., Vial, G., Demion, M., Blond, E., Zoulim, F., Gomez, L., Vidal, H., Lacampagne, A., and Ovize, M. (2012) Disruption of cyclophilin D-mediated calcium transfer from the ER to mitochondria contributes to hepatic ER stress and insulin resistance. Hepatology (In press)

45. Robert, M., Pelascini, E., Disse, E., Espalieu, P., Poncet, G., Laville, M., and Gouillat, C. (2012) Preoperative Fat-Free Mass: A Predictive Factor of Weight Loss after Gastric Bypass. Obes Surg (In press)

46. Schoppet, M., Hofbauer, L. C., Brinskelle-Schmal, N., Varennes, A., Goudable, J., Richard, M., Hawa, G., Chapurlat, R., and Szulc, P. (2012) Serum level of the phosphaturic factor FGF23 is associated with abdominal aortic calcification in men: the STRAMBO study. J Clin Endocrinol Metab 97, E575-583

47. Serdiuk, T., Alekseev, S. A., Lysenko, V., Skryshevsky, V. A., and Geloen, A. (2012) Charge-driven selective localization of fluorescent nanoparticles in live cells. Nanotechnology 23, 315101

48. Serdiuk, T., Lysenko, V., Mognetti, B., Skryshevsky, V., and Geloen, A. (2012) Impact of cell division on intracellular uptake and nuclear targeting with fluorescent SiC-based nanoparticles. J Biophotonics (In press)

49. Serdiuk, T., Lysenko, V., Skryshevsky, V. A., and Geloen, A. (2012) Vapor phase mediated cellular uptake of sub 5 nm nanoparticles. Nanoscale Res Lett 7, 212

50. Serdiuk, T., Zakharko, Y., Nychyporuk, T., Geloen, A., Lemiti, M., and Lysenko, V. (2012) Nanostructured silicon nitride thin films for label-free multicolor luminescent cell imaging. Nanoscale 4, 5860-5863

51. Soula, H. A., Coulon, A., and Beslon, G. (2012) Membrane microdomains emergence through non-homogeneous diffusion. BMC Biophys 5, 6

52. Tournadre, A., Lenief, V., Eljaafari, A., and Miossec, P. (2012) Immature muscle precursors are a source of interferon-beta in myositis: role of Toll-like receptor 3 activation and contribution to HLA class I up-regulation. Arthritis Rheum 64, 533-541

53. Volat, F. E., Pointud, J. C., Pastel, E., Morio, B., Sion, B., Hamard, G., Guichardant, M., Colas, R., Lefrancois-Martinez, A. M., and Martinez, A. (2012) Depressed levels of prostaglandin F2alpha in mice lacking Akr1b7 increase basal adiposity and predispose to diet-induced obesity. Diabetes 61, 2796-2806

2011

1. Blond, E., Maitrepierre, C., Normand, S., Goudable, J., Sothier, M., Roth, H., and Laville, M. (2011) A new indirect calorimeter is accurate and reliable for measuring basal energy expenditure, thermic effect of food and substrate oxidation in obese and healthy subjects. In e-SPEN, The European e-Journal of Clinical Nutrition and Metabolism Vol. 6 pp. e7-e15

2. Bonnet, F., Ducluzeau, P. H., Gastaldelli, A., Laville, M., Anderwald, C. H., Konrad, T., Mari, A., and Balkau, B. (2011) Liver enzymes are associated with hepatic insulin resistance, insulin secretion, and glucagon concentration in healthy men and women. Diabetes 60, 1660-1667

3. Bravard, A., Bonnard, C., Durand, A., Chauvin, M. A., Favier, R., Vidal, H., and Rieusset, J. (2011) Inhibition of xanthine oxidase reduces hyperglycemia-induced oxidative stress and improves mitochondrial alterations in skeletal muscle of diabetic mice. Am J Physiol Endocrinol Metab 300, E581-591

4. Bravard, A., Lefai, E., Meugnier, E., Pesenti, S., Disse, E., Vouillarmet, J., Peretti, N., Rabasa-Lhoret, R., Laville, M., Vidal, H., and Rieusset, J. (2011) FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction. Diabetes 60, 258-268

5. Care, B. R., and Soula, H. A. (2011) Impact of receptor clustering on ligand binding. BMC Syst Biol 5, 48

6. Cariou, B., Chetiveaux, M., Zair, Y., Pouteau, E., Disse, E., Guyomarc’h-Delasalle, B., Laville, M., and Krempf, M. (2011) Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults. Nutr Metab (Lond) 8, 48

7. Chaitou, A., Boutroy, S., Vilayphiou, N., Varennes, A., Richard, M., Blaizot, S., Munoz, F., Delmas, P. D., Goudable, J., Chapurlat, R., and Szulc, P. (2011) Association of bone microarchitecture with parathyroid hormone concentration and calcium intake in men: the STRAMBO study. Eur J Endocrinol 165, 151-159

8. Chouabe, C., Eyraud, V., Da Silva, P., Rahioui, I., Royer, C., Soulage, C., Bonvallet, R., Huss, M., and Gressent, F. (2011) New mode of action for a knottin protein bioinsecticide: pea albumin 1 subunit b (PA1b) is the first peptidic inhibitor of V-ATPase. J Biol Chem 286, 36291-36296

9. Coulon, A., Beslon, G., and Soula, H. A. (2011) Enhanced stimulus encoding capabilities with spectral selectivity in inhibitory circuits by STDP. Neural Comput 23, 882-908

10. Cour, M., Loufouat, J., Paillard, M., Augeul, L., Goudable, J., Ovize, M., and Argaud, L. (2011) Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study. Eur Heart J 32, 226-235

11. Cruiziat, C., Roman, S., Robert, M., Espalieu, P., Laville, M., Poncet, G., Gouillat, C., and Mion, F. (2011) High resolution esophageal manometry evaluation in symptomatic patients after gastric banding for morbid obesity. Dig Liver Dis 43, 116-120

12. Disse, E., Bussier, A. L., Deblon, N., Pfluger, P. T., Tschop, M. H., Laville, M., and Rohner-Jeanrenaud, F. (2011) Systemic ghrelin and reward: effect of cholinergic blockade. Physiol Behav 102, 481-484

13. Disse, E., Rabasa-Lhoret, R., Laville, M., and Bastard, J. P. (2011) Is it important to consider how hyperinsulinaemic-euglycaemic clamp results are expressed? Diabetes Metab 37, 460-461

14. Elie, J. E., Soula, H. A., Mathevon, N., and Vignal, C. (2011) Dynamics of communal vocalizations in a social songbird, the zebra finch (Taeniopygia guttata). J Acoust Soc Am 129, 4037-4046

15. Ferrannini, E., Natali, A., Muscelli, E., Nilsson, P. M., Golay, A., Laakso, M., Beck-Nielsen, H., Mari, A., and Laville, M. R. I. (2011) Natural history and physiological determinants of changes in glucose tolerance in a non-diabetic population: the RISC Study. Diabetologia 54, 1507-1516

16. Frojdo, S., Durand, C., Molin, L., Carey, A. L., El-Osta, A., Kingwell, B. A., Febbraio, M. A., Solari, F., Vidal, H., and Pirola, L. (2011) Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1. Mol Cell Endocrinol 335, 166-176

17. Gabert, L., Vors, C., Louche-Pelissier, C., Sauvinet, V., Lambert-Porcheron, S., Drai, J., Laville, M., Desage, M., and Michalski, M. C. (2011) 13C tracer recovery in human stools after digestion of a fat-rich meal labelled with [1,1,1-13C3]tripalmitin and [1,1,1-13C3]triolein. Rapid Commun Mass Spectrom 25, 2697-2703

18. Georges, A., Charrie, A., Raynaud, S., Lombard, C., and Corcuff, J. B. (2011) Thyroxin overdose due to rheumatoid factor interferences in thyroid-stimulating hormone assays. Clin Chem Lab Med 49, 873-875

19. Ibrahim, M. M., Fjaere, E., Lock, E. J., Naville, D., Amlund, H., Meugnier, E., Le Magueresse Battistoni, B., Froyland, L., Madsen, L., Jessen, N., Lund, S., Vidal, H., and Ruzzin, J. (2011) Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice. PLoS One 6, e25170

20. Jaafar, R., Zeiller, C., Pirola, L., Di Grazia, A., Naro, F., Vidal, H., Lefai, E., and Nemoz, G. (2011) Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes. J Biol Chem 286, 22609-22621

21. Jean, G., Lataillade, D., Genet, L., Legrand, E., Kuentz, F., Moreau-Gaudry, X., and Fouque, D. (2011) Association between very low PTH levels and poor survival rates in haemodialysis patients: results from the French ARNOS cohort. Nephron Clin Pract 118, c211-216

22. Jean, G., Lataillade, D., Genet, L., Legrand, E., Kuentz, F., Moreau-Gaudry, X., and Fouque, D. (2011) Impact of hypovitaminosis D and alfacalcidol therapy on survival of hemodialysis patients: results from the French ARNOS study. Nephron Clin Pract 118, c204-210

23. Jiao, H., Arner, P., Dickson, S. L., Vidal, H., Mejhert, N., Henegar, C., Taube, M., Hansson, C., Hinney, A., Galan, P., Simon, C., Silveira, A., Benrick, A., Jansson, J. O., Bouloumie, A., Langin, D., Laville, M., Debard, C., Axelsson, T., Ryden, M., Kere, J., Dahlman-Wright, K., Hamsten, A., Clement, K., and Dahlman, I. (2011) Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity. J Clin Endocrinol Metab 96, E962-966

24. Kalbacher, E., Koppe, L., Zarrouki, B., Pillon, N. J., Fouque, D., and Soulage, C. O. (2011) Human uremic plasma and not urea induces exuberant secretion of leptin in 3T3-L1 adipocytes. J Ren Nutr 21, 72-75

25. Laugerette, F., Vors, C., Geloen, A., Chauvin, M. A., Soulage, C., Lambert-Porcheron, S., Peretti, N., Alligier, M., Burcelin, R., Laville, M., Vidal, H., and Michalski, M. C. (2011) Emulsified lipids increase endotoxemia: possible role in early postprandial low-grade inflammation. J Nutr Biochem 22, 53-59

26. Le Goaziou, M. F., Contardo, G., Dupraz, C., Martin, A., Laville, M., and Schott-Pethelaz, A. M. (2011) Risk factors for vitamin D deficiency in women aged 20-50 years consulting in general practice: a cross-sectional study. Eur J Gen Pract 17, 146-152

27. Leal, V. O., Stockler-Pinto, M. B., Farage, N. E., Aranha, L. N., Fouque, D., Anjos, L. A., and Mafra, D. (2011) Handgrip strength and its dialysis determinants in hemodialysis patients. Nutrition 27, 1125-1129

28. Leenhardt, L., Borson-Chazot, F., Calzada, M., Carnaille, B., Charrie, A., Cochand-Priollet, B., Cao, C. D., Leboulleux, S., Le Clech, G., Mansour, G., Menegaux, F., Monpeyssen, H., Orgiazzi, J., Rouxel, A., Sadoul, J. L., Schlumberger, M., Tramalloni, J., Tranquart, F., and Wemeau, J. L. (2011) Good practice guide for cervical ultrasound scan and echo-guided techniques in treating differentiated thyroid cancer of vesicular origin. Ann Endocrinol (Paris) 72, 173-197

29. Lemoine, S., Papillard, M., Belloi, A., Rognant, N., Fouque, D., Laville, M., Rouviere, O., and Juillard, L. (2011) Renal perfusion: noninvasive measurement with multidetector CT versus fluorescent microspheres in a pig model. Radiology 260, 414-420

30. Levy, E., Harmel, E., Laville, M., Sanchez, R., Emonnot, L., Sinnett, D., Ziv, E., Delvin, E., Couture, P., Marcil, V., and Sane, A. T. (2011) Expression of Sar1b enhances chylomicron assembly and key components of the coat protein complex II system driving vesicle budding. Arterioscler Thromb Vasc Biol 31, 2692-2699

31. Mafra, D., Deleaval, P., Teta, D., Cleaud, C., Arkouche, W., Jolivot, A., and Fouque, D. (2011) Influence of inflammation on total energy expenditure in hemodialysis patients. J Ren Nutr 21, 387-393

32. Manfo, F. P., Chao, W. F., Moundipa, P. F., Pugeat, M., and Wang, P. S. (2011) Effects of maneb on testosterone release in male rats. Drug Chem Toxicol 34, 120-128

33. Mari, A., Tura, A., Natali, A., Anderwald, C., Balkau, B., Lalic, N., Walker, M., Ferrannini, E., and Laville, M. R. I. (2011) Influence of hyperinsulinemia and insulin resistance on in vivo beta-cell function: their role in human beta-cell dysfunction. Diabetes 60, 3141-3147

34. Meugnier, E., Coury, F., Tebib, J., Ferraro-Peyret, C., Rome, S., Bienvenu, J., Vidal, H., Sibilia, J., and Fabien, N. (2011) Gene expression profiling in peripheral blood cells of patients with rheumatoid arthritis in response to anti-TNF-alpha treatments. Physiol Genomics 43, 365-371

35. Moreau-Gaudry, X., Guebre-Egziabher, F., Jean, G., Genet, L., Lataillade, D., Legrand, E., Kuentz, F., Trolliet, P., and Fouque, D. (2011) Serum creatinine improves body mass index survival prediction in hemodialysis patients: a 1-year prospective cohort analysis from the ARNOS study. J Ren Nutr 21, 369-375

36. Naville, D., Rebourcet, D., Chauvin, M. A., Vega, N., Jalabert, A., Vigier, M., Loizon, E., Begeot, M., and Le Magueresse-Battistoni, B. (2011) Direct and indirect impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on adult mouse Leydig cells: an in vitro study. Toxicol Lett 207, 251-257

37. Nazare, J. A., Sauvinet, V., Normand, S., Guerin-Deremaux, L., Gabert, L., Desage, M., Wils, D., and Laville, M. (2011) Impact of a resistant dextrin with a prolonged oxidation pattern on day-long ghrelin profile. J Am Coll Nutr 30, 63-72

38. Pelletier, S., and Fouque, D. (2011) Mineral and bone metabolism in dialysis: towards unified patient care? Nephrol Dial Transplant 26, 7-9

39. Pillon, N. J., Vella, R. E., Souleere, L., Becchi, M., Lagarde, M., and Soulage, C. O. (2011) Structural and functional changes in human insulin induced by the lipid peroxidation byproducts 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal. Chem Res Toxicol 24, 752-762

40. Pillot, B., Duraffourd, C., Begeot, M., Joly, A., Luquet, S., Houberdon, I., Naville, D., Vigier, M., Gautier-Stein, A., Magnan, C., and Mithieux, G. (2011) Role of hypothalamic melanocortin system in adaptation of food intake to food protein increase in mice. PLoS One 6, e19107

41. Pirola, L., Balcerczyk, A., Tothill, R. W., Haviv, I., Kaspi, A., Lunke, S., Ziemann, M., Karagiannis, T., Tonna, S., Kowalczyk, A., Beresford-Smith, B., Macintyre, G., Kelong, M., Hongyu, Z., Zhu, J., and El-Osta, A. (2011) Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells. Genome Res 21, 1601-1615

42. Rebelos, E., Muscelli, E., Natali, A., Balkau, B., Mingrone, G., Piatti, P., Konrad, T., Mari, A., Ferrannini, E., and Laville, M. R. I. (2011) Body weight, not insulin sensitivity or secretion, may predict spontaneous weight changes in nondiabetic and prediabetic subjects: the RISC study. Diabetes 60, 1938-1945

43. Rognant, N., Guebre-Egziabher, F., Bacchetta, J., Janier, M., Hiba, B., Langlois, J. B., Gadet, R., Laville, M., and Juillard, L. (2011) Evolution of renal oxygen content measured by BOLD MRI downstream a chronic renal artery stenosis. Nephrol Dial Transplant 26, 1205-1210

44. Rognant, N., Lemoine, S., Laville, M., Hadj-Aissa, A., and Dubourg, L. (2011) Performance of the chronic kidney disease epidemiology collaboration equation to estimate glomerular filtration rate in diabetic patients. Diabetes Care 34, 1320-1322

45. Sauvinet, V., Gabert, L., Alligier, M., Normand, S., Roth, H., Laville, M., and Desage, M. (2011) Comparison of high-temperature conversion and equilibration methods for the determination of d31-palmitic acid oxidation in man using continuous-flow isotope ratio mass spectrometry. Rapid Commun Mass Spectrom 25, 2749-2759

46. Teta, D., and Fouque, D. (2011) Renal nutrition: progress on fast track. J Ren Nutr 21, 1

47. Vangipurapu, J., Stancakova, A., Kuulasmaa, T., Paananen, J., Kuusisto, J., Ferrannini, E., Laakso, M., and Laville, M. E.-R. S. g. (2011) A novel surrogate index for hepatic insulin resistance. Diabetologia 54, 540-543

48. Zitt, E., Rix, M., Urena Torres, P., Fouque, D., Jacobson, S. H., Petavy, F., Dehmel, B., and Ryba, M. (2011) Effectiveness of cinacalcet in patients with recurrent/persistent secondary hyperparathyroidism following parathyroidectomy: results of the ECHO study. Nephrol Dial Transplant 26, 1956-1961

2010

1. Bacchetta, J., Boutroy, S., Vilayphiou, N., Fouque-Aubert, A., Delmas, P. D., Lespessailles, E., Fouque, D., and Chapurlat, R. (2010) Assessment of bone microarchitecture in chronic kidney disease: a comparison of 2D bone texture analysis and high-resolution peripheral quantitative computed tomography at the radius and tibia. Calcif Tissue Int 87, 385-391

2. Bacchetta, J., Boutroy, S., Vilayphiou, N., Juillard, L., Guebre-Egziabher, F., Rognant, N., Sornay-Rendu, E., Szulc, P., Laville, M., Delmas, P. D., Fouque, D., and Chapurlat, R. (2010) Early impairment of trabecular microarchitecture assessed with HR-pQCT in patients with stage II-IV chronic kidney disease. J Bone Miner Res 25, 849-857

3. Bacchetta, J., Fargue, S., Boutroy, S., Basmaison, O., Vilayphiou, N., Plotton, I., Guebre-Egziabher, F., Dohin, B., Kohler, R., and Cochat, P. (2010) Bone metabolism in oxalosis: a single-center study using new imaging techniques and biomarkers. Pediatr Nephrol 25, 1081-1089

4. Berger, E., Rome, S., Vega, N., Ciancia, C., and Vidal, H. (2010) Transcriptome profiling in response to adiponectin in human cancer-derived cells. Physiol Genomics 42A, 61-70

5. Bonnefoy, M., Laville, M., Ecochard, R., Jusot, J. F., Normand, S., Maillot, S., Lebreton, B., and Jauffret, M. (2010) Effects of branched amino acids supplementation in malnourished elderly with catabolic status. J Nutr Health Aging 14, 579-584

6. Bournaud, C., Charrie, A., Nozieres, C., Chikh, K., Lapras, V., Denier, M. L., Paulin, C., Decaussin-Petrucci, M., Peix, J. L., Lifante, J. C., Cornu, C., Giraud, C., Orgiazzi, J., and Borson-Chazot, F. (2010) Thyroglobulin measurement in fine-needle aspirates of lymph nodes in patients with differentiated thyroid cancer: a simple definition of the threshold value, with emphasis on potential pitfalls of the method. Clin Chem Lab Med 48, 1171-1177

7. Calzada, C., Colas, R., Guillot, N., Guichardant, M., Laville, M., Vericel, E., and Lagarde, M. (2010) Subgram daily supplementation with docosahexaenoic acid protects low-density lipoproteins from oxidation in healthy men. Atherosclerosis 208, 467-472

8. Cavret, S., Laurent, N., Videmann, B., Mazallon, M., and Lecoeur, S. (2010) Assessment of deoxynivalenol (DON) adsorbents and characterisation of their efficacy using complementary in vitro tests. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 27, 43-53

9. Colas, R., Pruneta-Deloche, V., Guichardant, M., Luquain-Costaz, C., Cugnet-Anceau, C., Moret, M., Vidal, H., Moulin, P., Lagarde, M., and Calzada, C. (2010) Increased lipid peroxidation in LDL from type-2 diabetic patients. Lipids 45, 723-731

10. Covic, A., Bammens, B., Lobbedez, T., Segall, L., Heimburger, O., van Biesen, W., Fouque, D., and Vanholder, R. (2010) Educating end-stage renal disease patients on dialysis modality selection: clinical advice from the European Renal Best Practice (ERBP) Advisory Board. Nephrol Dial Transplant 25, 1757-1759

11. Cugnet-Anceau, C., Nazare, J. A., Biorklund, M., Le Coquil, E., Sassolas, A., Sothier, M., Holm, J., Landin-Olsson, M., Onning, G., Laville, M., and Moulin, P. (2010) A controlled study of consumption of beta-glucan-enriched soups for 2 months by type 2 diabetic free-living subjects. Br J Nutr 103, 422-428

12. Disse, E., Bussier, A. L., Veyrat-Durebex, C., Deblon, N., Pfluger, P. T., Tschop, M. H., Laville, M., and Rohner-Jeanrenaud, F. (2010) Peripheral ghrelin enhances sweet taste food consumption and preference, regardless of its caloric content. Physiol Behav 101, 277-281

13. Dray, C., Debard, C., Jager, J., Disse, E., Daviaud, D., Martin, P., Attane, C., Wanecq, E., Guigne, C., Bost, F., Tanti, J. F., Laville, M., Vidal, H., Valet, P., and Castan-Laurell, I. (2010) Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans. Am J Physiol Endocrinol Metab 298, E1161-1169

14. Eyenga, P., Lhuillier, F., Morel, J., Roussel, D., Sibille, B., Letexier, D., Cespuglio, R., Duchamp, C., Goudable, J., Bricca, G., and Viale, J. P. (2010) Time course of liver nitric oxide concentration in early septic shock by cecal ligation and puncture in rats. Nitric Oxide 23, 194-198

15. Gauchez, A. S., Pizzo, M., Alcaraz-Galvain, D., Chikh, K., Orgiazzi, J., Brabant, G., Ronin, C., and Charrie, A. (2010) TSH Isoforms: About a Case of Hypothyroidism in a Down’s Syndrome Young Adult. J Thyroid Res 2010, 703978

16. Giroud, S., Perret, M., Stein, P., Goudable, J., Aujard, F., Gilbert, C., Robin, J. P., Le Maho, Y., Zahariev, A., Blanc, S., and Momken, I. (2010) The grey mouse lemur uses season-dependent fat or protein sparing strategies to face chronic food restriction. PLoS One 5, e8823

17. Gout, J., Sarafian, D., Mutel, E., Vigier, M., Rajas, F., Mithieux, G., Begeot, M., and Naville, D. (2010) Metabolic and melanocortin gene expression alterations in male offspring of obese mice. Mol Cell Endocrinol 319, 99-108

18. Hanf, W., Guillaume, C., Jolivot, A., Chapuis-Cellier, C., Guebre-Egziabher, F., Fontana, A., Fouque, D., and Juillard, L. (2010) Prolonged hemodialysis for acute kidney injury in myeloma patients. Clin Nephrol 74, 319-322

19. Jager, J., Gremeaux, T., Gonzalez, T., Bonnafous, S., Debard, C., Laville, M., Vidal, H., Tran, A., Gual, P., Le Marchand-Brustel, Y., Cormont, M., and Tanti, J. F. (2010) Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis. Diabetes 59, 61-70

20. Kozakova, M., Palombo, C., Morizzo, C., Nolan, J. J., Konrad, T., Balkau, B., and Laville, M. R. I. (2010) Effect of sedentary behaviour and vigorous physical activity on segment-specific carotid wall thickness and its progression in a healthy population. Eur Heart J 31, 1511-1519

21. Lecomte, V., Meugnier, E., Euthine, V., Durand, C., Freyssenet, D., Nemoz, G., Rome, S., Vidal, H., and Lefai, E. (2010) A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation. Mol Cell Biol 30, 1182-1198

22. Lefils, J., Geloen, A., Vidal, H., Lagarde, M., and Bernoud-Hubac, N. (2010) Dietary DHA: time course of tissue uptake and effects on cytokine secretion in mice. Br J Nutr 104, 1304-1312

23. Lobo, J. C., Torres, J. P., Fouque, D., and Mafra, D. (2010) Zinc deficiency in chronic kidney disease: is there a relationship with adipose tissue and atherosclerosis? Biol Trace Elem Res 135, 16-21

24. Mafra, D., Guebre-Egziabher, F., Cleaud, C., Arkouche, W., Mialon, A., Drai, J., and Fouque, D. (2010) Obestatin and ghrelin interplay in hemodialysis patients. Nutrition 26, 1100-1104

25. Mafra, D., Guebre-Egziabher, F., and Fouque, D. (2010) Endocrine role of stomach in appetite regulation in chronic kidney disease: about ghrelin and obestatin. J Ren Nutr 20, 68-73

26. Mafra, D., Jolivot, A., Chauveau, P., Drai, J., Azar, R., Michel, C., and Fouque, D. (2010) Are ghrelin and leptin involved in food intake and body mass index in maintenance hemodialysis? J Ren Nutr 20, 151-157

27. Mari, A., Tura, A., Natali, A., Laville, M., Laakso, M., Gabriel, R., Beck-Nielsen, H., and Ferrannini, E. (2010) Impaired beta cell glucose sensitivity rather than inadequate compensation for insulin resistance is the dominant defect in glucose intolerance. Diabetologia 53, 749-756

28. Mazaud-Guittot, S., Meugnier, E., Pesenti, S., Wu, X., Vidal, H., Gow, A., and Le Magueresse-Battistoni, B. (2010) Claudin 11 deficiency in mice results in loss of the Sertoli cell epithelial phenotype in the testis. Biol Reprod 82, 202-213

29. Mognetti, B., Barberis, A., Marino, S., Di Carlo, F., Lysenko, V., Marty, O., and Geloen, A. (2010) Preferential killing of cancer cells using silicon carbide quantum dots. J Nanosci Nanotechnol 10, 7971-7975

30. Nazare, J. A., de Rougemont, A., Normand, S., Sauvinet, V., Sothier, M., Vinoy, S., Desage, M., and Laville, M. (2010) Effect of postprandial modulation of glucose availability: short- and long-term analysis. Br J Nutr 103, 1461-1470

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