Publications CarMeN de juillet à septembre 2025

Juillet 2025

Aouifi, A., Faraoni, D., Keller, G., Ketels, F., Raspado, O., Lapeze, J. and Farhat, F. Erythrocytes and Platelets Autotransfusion in High Hemorrhagic Risk Cardiac Surgery: A Single-Center Pilot Analysis of the Multicentric SEPIA Registry Anesth Analg. 2025 Jul 1;141(1). doi: 10.1213/ane.0000000000007374.

Bardet, A., Vincent, M., Portefaix, A., Claris, O., Butin, M., Patural, H., Picaud, J. C., Chevallier, M., Perge, K., Raverot, V., Riche, B. and Bretones, P. Treatment of Transient Hypothyroxinemia of Prematurity Does Not Improve Neurodevelopment at Two Years of Age Acta Paediatr. 2025 Jul;114(7). doi: 10.1111/apa.17610.

Berdot, S., Perrin, G., Disse, E., Arnoux, A., Bertin, E., Borel, A. L., Brindisi, M. C., De Luca, A., Laforgue, E. J., Lalau, J. D., Matussiere, Y., Montastier, E., Sallé, A., Segrestin, B., Suteau, V., Czernichow, S. and Sabatier, B. Delphi Consensus Among French Obesity Experts on Clinical Recommendations for Drug Prescription in Patients With Severe Obesity Obes Rev. 2025 Jul 8;doi: 10.1111/obr.13977.

Bollon, T., Jobbe-Duval, A., Mewton, N., Sebbag, L., Bouali, A., Harbaoui, B., Lantelme, P., Thibault, H. and Courand, P. Y. Left atrial strain reservoir in amyloid cardiomyopathy: A strong predictor of mid-term incident atrial fibrillation Arch Cardiovasc Dis. 2025 Jul 2;doi: 10.1016/j.acvd.2025.06.070.

Bourdier, P., Devitt, J., Gallon, S., Zahariev, A., Chery, I., Guzzetti, J. R., Blanc, S., Simon, C. and Bergouignan, A. Energy balance in women during polar trekking-The POWER study Physiol Rep. 2025 Jul;13(13). doi: 10.14814/phy2.70443.

Brown, A. S., Moulin, P., Dibble, A., Alexander, V. J., Li, L., Gaudet, D., Witztum, J. L., Tsimikas, S. and Hegele, R. A. Brief communication: Strong concordance of the North American Familial Chylomicronemia Syndrome Score with a positive genetic diagnosis in patients from the Balance study J Clin Lipidol. 2025 Jul 23;doi: 10.1016/j.jacl.2025.07.008.

Costes-Albrespic, M., Alencar de Pinho, N., Larabi, I. A., El Chamieh, C., Laville, S. M., Fouque, D., Laville, M., Frimat, L., Alvarez, J. C., Massy, Z. A. and Liabeuf, S. Furosemide and Serum Protein-Bound Uremic Toxin Concentrations in Patients With CKD Kidney Int Rep. 2025 Jul;10(7). doi: 10.1016/j.ekir.2025.04.040.

d’Entremont, M. A., Poorthuis, M. H. F., Fiolet, A. T. L., Amarenco, P., Boczar, K. E., Buysschaert, I., Chan, N. C., Cornel, J. H., Jannink, J., Jansen, S., Kedev, S., Keech, A. C., Layland, J., Mewton, N., Montalescot, G., Pascual-Figal, D. A., Rodriguez, A. E., Shah, B., Teraa, M., van Zelm, A., Wang, Y., Mosterd, A., Kelly, P., Eikelboom, J. and Jolly, S. S. Colchicine for secondary prevention of vascular events: a meta-analysis of trials Eur Heart J. 2025 Jul 7;46(26). doi: 10.1093/eurheartj/ehaf210.

Dumortier, J., Hamada, S., Wischlen, E., Mandier, C., Laverdure, N., Boillot, O., Kounis, I., Allain, V., Hervieu, V., Collardeau-Frachon, S., Dubois, V. and Feray, C. Donor HLA Class I Evolutionary Divergence and Late Allograft Rejection After Liver Transplantation in Children: An Emulated Target Trial Hla. 2025 Jul;106(1). doi: 10.1111/tan.70320.

Geri, G., Lascarrou, J. B., Levy, B., Asfar, P., Muller, G., Legriel, S., Ricôme, S., Cour, M., Klouche, K., Sauneuf, B., Quenot, J. P., Bougouin, W. and Cariou, A. Hydrocortisone and arginine vasopressin in post-resuscitation shock: the HYVAPRESS trial Resusc Plus. 2025 Jul;24(doi: 10.1016/j.resplu.2025.100982.

Holle, J., Behrens, F. and Koppe, L. Pediatric and adult point of view on the gut-kidney axis in CKD Pediatr Nephrol. 2025 Jul 7;doi: 10.1007/s00467-025-06780-8.

Jacquet-Lagrèze, M., Ruste, M., Noumedem, E., Bouhamri, N., Portran, P. and Fellahi, J. L. Gingival capillary refill time: a new approach to assess tissue perfusion Crit Care. 2025 Jul 28;29(1). doi: 10.1186/s13054-025-05555-9.

Khanafer, N., Lukaszewicz, A. C., Kuczewski, E., Argaud, L. and Vanhems, P. Epidemiology and Impact of Staff Training in Controlling Complications Related to Central Venous Catheters in 4 Intensive Care Units in a French University Hospital: Protocol of a Prospective, Quasi-Experimental, Before-After Study JMIR Res Protoc. 2025 Jul 23;14(doi: 10.2196/74985.

Larouche, M., Bergeron, J., Brisson, D., Laflamme, N., Audet-Verreault, N., Sharon, C., Charrière, S., Rama, M., Collin-Chavagnac, D., Moulin, P. and Gaudet, D. Course of Pregnancies and Occurrence of Acute Pancreatitis in Women with Chylomicronemia J Clin Endocrinol Metab. 2025 Jul 15;doi: 10.1210/clinem/dgaf409.

Laville, S. M., Mouheb, A., Massy, Z. A., Jacquelinet, C., Laville, M., Stengel, B., de Pinho, N. A. and Liabeuf, S. Male and female drug prescription patterns and adverse drug reactions in chronic kidney disease Nephrol Dial Transplant. 2025 Jul 4;doi: 10.1093/ndt/gfaf125.

Lazarus, J. V., Brennan, P. N., Mark, H. E., Alazawi, W., Allen, A. M., Byrne, C. D., Castera, L., Caussy, C., Cusi, K., Grajower, M. M., Kopka, C. J., Massoels, J., Roden, M., Spearman, C. W., Tacke, F., Wong, V. W. and Noureddin, M. A call for doubling the diagnostic rate of at-risk metabolic dysfunction-associated steatohepatitis Lancet Reg Health Eur. 2025 Jul;54(doi: 10.1016/j.lanepe.2025.101320.

Ludwig, S., Coisne, A., Hamzi, K., Ben Ali, W., Scotti, A., Koell, B., Duncan, A., Makkar, R., Akodad, M., Bleiziffer, S., Nickenig, G., Kaneko, T., Ruge, H., Adam, M., Sondergaard, L., Dahle, G., Taramasso, M., Walther, T., Kempfert, J., Obadia, J. F., Chehab, O., Tang, G. H. L., Goel, S., Fam, N., Denti, P., Praz, F., von Bardeleben, R. S., Hausleiter, J., Latib, A., Conradi, L., Modine, T., Pezel, T. and Granada, J. F. Phenotypic clustering analysis of patients rejected for mitral valve interventions: implications for future transcatheter technologies Eur Heart J Cardiovasc Imaging. 2025 Jul 31;26(8). doi: 10.1093/ehjci/jeaf141.

Montégut, C., Falandry, C., Cinieri, S., Cropet, C., Montane, L., Rousseau, F., Joly, F., Moubarak, M., Mosconi, A. M., Guerra-Alía, E. M., Schauer, C., Fujiwara, H., Vergote, I., Parma, G., Lindahl, G., Anota, A., Canzler, U., Marmé, F., Pujade-Lauraine, E., Ray-Coquard, I. and Sabatier, R. Safety and quality of life with maintenance olaparib plus bevacizumab in older patients with ovarian cancer: subgroup analysis of PAOLA‑1/ENGOT-ov25 Oncologist. 2025 Jul 4;30(7). doi: 10.1093/oncolo/oyae322.

Nägele, F. L., Scheldeman, L., Wouters, A., Heinze, M., Petersen, M., Schlemm, E., Schell, M., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Galinovic, I., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Puig, J., Simonsen, C. Z., Thijs, V., Thomalla, G. and Cheng, B. Blood-Brain Barrier Leakage in the Penumbra Is Associated With Infarction on Follow-Up Imaging in Acute Ischemic Stroke Stroke. 2025 Jul;56(7). doi: 10.1161/strokeaha.124.050171.

Noone, J., Damiot, A., Kenny, H., Chery, I., Zahariev, A., Normand, S., Crampes, F., de Glisezinski, I., Rochfort, K. D., Laurens, C., Bareille, M. P., Simon, C., Bergouignan, A., Blanc, S. and O’Gorman, D. J. The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics J Physiol. 2025 Jul;603(13). doi: 10.1113/jp284734.

Quintin, J., Le Thuaut, A., Plouvier, F., Zerbib, Y., Sirodot, M., Sedillot, N., de Longeaux, K., Le Meur, A., Souweine, B., Quenot, J. P., Lacherade, J. C., Noublanche, J., Landais, M., Thevenin, D., Nseir, S., Lafon, T., Vanderlinden, T., Smonig, R., Argaud, L., Chauvelot, L., Dubois, M., Larcher, R., Berteau, F., Dellamonica, J., Barbar, S., Serie, M., Kamel, T., Jacobs, F., De Prost, N., Devaquet, J., Heming, N., Pineton De Chambrun, M., Michel, P., Djibre, M., Ferre, A., Picard, W., Pinceaux, K., Tamion, F., Legay, F., Jonas, M., Curtiaud, A., Ehrmann, S., Huntzinger, J., Cracco, C., Schortgen, F., Letocart, P. and Reignier, J. Characteristics and outcomes of ICU patients with sepsis transmitted by cats and dogs: the PETSEPSIS multicentre retrospective observational cohort study Crit Care. 2025 Jul 22;29(1). doi: 10.1186/s13054-025-05558-6.

Sotin, T., Ge, X., Schönke, M., Vince, L., Thouzeau, A., Frey, S., Lorant, V., Krul, L., Pronk, A. C. M., Lalai, R., Streefland, T. C. M., Afkir, S., Dijk, W., Smati, S., Heijink, M., Blomberg, N., Giera, M., Di Filippo, M., Moulin, P., Kooijman, S., Cariou, B., Rensen, P. C. N. and Le May, C. A rare gain of function variant of hepatic lipase attenuates hypercholesterolaemia and atherosclerosis in mice via an LDL receptor-independent mechanism Cardiovasc Res. 2025 Jul 8;121(7). doi: 10.1093/cvr/cvaf097.

Thivolet, C., Henry, Z., Bendelac, N. and Fimbel, S. V. Body weight trends in individuals with type 1 diabetes using automated insulin delivery vs. traditional insulin pumps Diabetes Metab. 2025 Jul 29;51(6). doi: 10.1016/j.diabet.2025.101693.

Trenchat, L., Galerneau, L. M., Ruckly, S., Sigaud, F., Terzi, N., Garrouste, M., Oziel, J., Hong Tuan Ha, V., Gainnier, M., Siami, S., Dartevel, A., Dupuis, C., Forel, J. M., Dessajan, J., Adrie, C., Goldgran-Toledano, D., Laurent, V., Argaud, L., Reignier, J., Dumas, G., Darmon, M. and Timsit, J. F. Self-extubation in critically ill patients: from the French OUTCOMEREA Network Crit Care. 2025 Jul 7;29(1). doi: 10.1186/s13054-025-05472-x.

Urbain, J., Beltramin, D., Shipkov, H., Ospital, C., Lherm, M., Mojallal, A. and Boucher, F. Thoracoabdominal advancement flap for definition of inframammary fold in delayed breast reconstruction: A retrospective cohort study assessing safety and patient-reported satisfaction using the BREAST-Q J Plast Reconstr Aesthet Surg. 2025 Jul;106(doi: 10.1016/j.bjps.2025.04.049.

 

Août 2025

Atallah, A., Sarda, M. N., McCarey, C., Massardier, J. and Huissoud, C. Endothelial Glycocalyx: The Missing Link Between Angiogenic Imbalance in Preeclampsia and Systemic Inflammation in HELLP Syndrome Compr Physiol. 2025 Aug;15(4). doi: 10.1002/cph4.70032.

Azoulay, É., Argaud, L., Labbé, V., Dumas, G., Bruneel, F., Jourdain, M., Guitton, C., Seguin, A., Jaber, S., Schnell, D., Vinatier, I., Ardisson, F., Ramakers, M., Herault, A., Lesieur, O., Cariou, A., Vieillard-Baron, A., Guisset, O., Pochard, F., Darmon, M. and Kentish-Barnes, N. Posttraumatic Growth in Intensive Care Unit Health Care Professionals After COVID-19 JAMA Netw Open. 2025 Aug 1;8(8). doi: 10.1001/jamanetworkopen.2025.27443.

Benzakoun, J., Scheldeman, L., Wouters, A., Cheng, B., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Galinovic, I., Muir, K. W., Nighoghossian, N., Pedraza, S., Puig, J., Simonsen, C. Z., Thijs, V., Thomalla, G., Micard, E., Chen, B., Lapergue, B., Boulouis, G., Le Berre, A., Baron, J. C., Turc, G., Ben Hassen, W., Naggara, O., Oppenheim, C. and Lemmens, R. Automated DWI-FLAIR mismatch assessment in stroke using DWI only Eur Stroke J. 2025 Aug 28;doi: 10.1177/23969873251362712.

Bidar, F., Jacquet-Lagreze, M., Bouisset, B., Fellahi, J. L. and Rimmelé, T. Safely combining renal replacement therapy and extracorporeal membrane oxygenation Anaesth Crit Care Pain Med. 2025 Aug 11;44(5). doi: 10.1016/j.accpm.2025.101599.

Boiteux, C., Chauveau, S., Gardey, K., Sebbag, L., Ditac, G., Cazeneuve, C., Mewton, N., Janin, A., Chevalier, P. and Delinière, A. Arrhythmogenic Cardiomyopathy Is a New Phenotype Associated With the CACNA1C p.Arg518Cys (R518C) Variant JACC Clin Electrophysiol. 2025 Aug 20;doi: 10.1016/j.jacep.2025.06.039.

Brasme, R., Candellier, A., Wetzstein, M., Schleef, M., Urena-Torres, P., Moret, L., Estournet, C., Coliche, V., Darres, A., Testa, A., Maisonneuve, N. and Hennino, M. F. Recurrence of CKD-associated pruritus after discontinuation of difelikefalin Nephrol Dial Transplant. 2025 Aug 29;40(9). doi: 10.1093/ndt/gfaf081.

Caprice-Grabiaud, K., Prezelin-Reydit, M., Guerraoui, A., Dolley-Hitze, T., Gosselin, M., Vendrely, B., Hallonet, P., Pelletier, S., Delizre, A., Duneau, G., Fessi, A., Kolko, A., Bouiller, M., Hirigoyen, M. D., Azzouz, L., Fouque, D., Vigneau, C., Pinçon, É., Duquennoy, S., Chantrel, F., Combe, C., Chauveau, P., Caillette-Beaudoin, A., Lasseur, C., Rascle, N. and Idier, L. [Evolution of the psychological repercussions of the COVID-19 pandemic on hemodialysis patients and caregivers between April 2020 and April 2022] Nephrol Ther. 2025 Aug 7;21(4). doi: 10.1684/ndt.2025.131.

Cariou, B. and Moulin, P. Obicetrapib and CETP inhibition: An exception to the rule? Med. 2025 Aug 8;6(8). doi: 10.1016/j.medj.2025.100780.

Courtay-Breuil, A., Delaire, L., Humblot, J., Gilbert, T., Aubertin-Leheudre, M. and Bonnefoy, M. Influence of a multicomponent exercise intervention on fear of falling and gait parameters in community-dwelling older adults: a prospective study BMC Geriatr. 2025 Aug 28;25(1). doi: 10.1186/s12877-025-06257-1.

Criton, G., Hermier, M., de Bourguignon, C., Mechtouff, L., Gamondès, D., Martin, A., Jupin-Delevaux, E., Cho, T. H., Derex, L., Clottes, P., Ong, E., Nighoghossian, N., Berthezene, Y. and Bani-Sadr, A. The Brush Sign Is Associated with a More Severe Oxygen Metabolic Impairment of the Ischemic Penumbra: An MRI-Based Study in Patients with Acute Stroke AJNR Am J Neuroradiol. 2025 Aug 1;46(8). doi: 10.3174/ajnr.A8723.

Dargent, A., Fournel, I., Jacquier, M., Dumargne, H., Argaud, L. and Quenot, J. P. Subcutaneous interstitial pressure measurement during early septic shock: an exploratory study Sci Rep. 2025 Aug 27;15(1). doi: 10.1038/s41598-025-15813-z.

de Castro Trigueira, P., Coutinho-Wolino, K. S., Brito, M. L., de Oliveira Leal, V., de França Cardozo, L. F. M., Fouque, D., Mafra, D. and Barcza Stockler-Pinto, M. Effects of dietary compounds on nuclear factor erythroid 2-related factor 2 (Nrf2) modulation in chronic kidney disease: a systematic review of clinical trials Crit Rev Food Sci Nutr. 2025 Aug;65(21). doi: 10.1080/10408398.2024.2384658.

Dérimay, F., Issa, R., Fort, J., Grinberg, D., Si-Mohamed, S. and Rioufol, G. Occlusion of Ventricular Septal Rupture With an Amulet Left Appendage Atrial Occluder Can J Cardiol. 2025 Aug;41(8). doi: 10.1016/j.cjca.2025.03.035.

Fauvel, C., Dillinger, J. G., Bochaton, T., Levasseur, T., El Ouahidi, A., Zakine, C., El Hadad, A., Mansencal, N., Noirclerc, N., Goralski, M., Thuaire, C., Mewton, N., Schurtz, G., Lim, P., Pommier, T., Lemarchand, L., Laissac, Q., Lamblin, N., Boukertouta, T., Logeart, D., Cohen-Solal, A., Henry, P. and Pezel, T. In-hospital and 1 year incremental prognostic value of drug abuse detection in acute heart failure ESC Heart Fail. 2025 Aug;12(4). doi: 10.1002/ehf2.15118.

Fielding, R. A., Rolland, Y., Bruyere, O., Desvarieux, M., Donini, L. M., Incalzi, R. A., Muscaritoli, M., Tchalla, A., Bonnefoy, M., Rondanelli, M., Van Maanen, R., Mariani, J., Margalef, C., Del Signore, S., Tourette, C., Dioh, W. and Veillet, S. Characterizing sarcopenia and sarcopenic obesity in patients aged 65 years and over, at risk of mobility disability: a multicenter observational trial (SARA-OBS) BMC Geriatr. 2025 Aug 4;25(1). doi: 10.1186/s12877-025-05895-9.

García-Arauzo, M., Reymond, S., Gruaz, L., Schvartz, D., Civic, N., Docquier, M., Deffert, C., Colosetti, P., Sanchez, J. C. and Bridel, C. Cerebrospinal Fluid-Derived Extracellular Vesicles: A Proteomic and Transcriptomic Comparative Analysis of Enrichment Protocols J Extracell Biol. 2025 Aug;4(8). doi: 10.1002/jex2.70076.

Harrison, F., Bella, S., Makki, K. and Dahan, N. A Near Catastrophe: Antiphospholipid Syndrome and Catastrophic Antiphospholipid Syndrome Complicating Emergency Department Care J Emerg Med. 2025 Aug;75(doi: 10.1016/j.jemermed.2025.05.012.

Heitzinger, G., Dreyfus, J., Dannenberg, V., Topilsky, Y., Benfari, G., Marsan, N. A., Taramasso, M., Russo, G., Bohbot, Y., Iliadis, C., Weber, M., Nombela-Franco, L., Eixerés-Esteve, A., Bazire, B., Iung, B., Obadia, J. F., Loureiro, R. E., Riant, E., Donal, E., Habib, G., Lavie-Badie, Y., Hausleiter, J., Stolz, L., Badano, L., Le Tourneau, T., Coisne, A., Modine, T., Praz, F., Zamorano, J. L., von Bardeleben, R. S., Hahn, R. T., Fam, N., Sievert, H., Muraru, D., Adamo, M., Heuts, S., Nejjari, M., Chan, V., De Bonis, M., Carnero-Alcazar, M., Rudolph, V., Crestanello, J., Lurz, P., Bax, J., Gauda, R., Bernick, J., Wells, G. A., Maisano, F., Enriquez-Sarano, M., Bartko, P. and Messika-Zeitoun, D. Left ventricular ejection fraction and benefit of tricuspid valve interventions – insights from the international TRIGISTRY Eur J Heart Fail. 2025 Aug 30;doi: 10.1002/ejhf.3797.

Kuzheleva, E., Saldarriaga, C., Mewton, N., Komarova, I., Mukhina, N., Cherkasova, N., Sitnikova, V., Anzhela, S., Novitsky, N., Baglikov, A., Dyachuk, I., Bibarsova, A., Rogova, A., Lezhneva, V., Stepanenko, E., Goldfeder de Gracia, S., Giverts, I., Tun, H. N., Suvorov, A., Marija, V., Mareev, Y. V., Imanov, G. and Shchendrygina, A. Assessment of regional variation in the management of heart failure with a preserved ejection fraction between the Russian Federation and the European Union: the results of the international survey BMJ Open. 2025 Aug 13;15(8). doi: 10.1136/bmjopen-2025-103134.

Lemoine, S., De Mul, A., Perge, K., Derain-Dubourg, L., Chapurlat, R., Vignot, E., Legrand, M. A. and Bacchetta, J. Challenges in Estimating Renal Function in X-linked Hypophosphatemia because of formula Overestimation and FGF23 Effects J Clin Endocrinol Metab. 2025 Aug 25;doi: 10.1210/clinem/dgaf459.

Levassort, H., Boucquemont, J., Liabeuf, S., Laville, S. M., Lange, C., Frimat, L., Combe, C., Fouque, D., Laville, M., Jacquelinet, C., Herpe, Y. E., Larabi, I. A., Alvarez, J. C., Alencar de Pinho, N., Pépin, M. and Massy, Z. A. Association of Phenylacetylglutamine and Cognitive Impairment in CKD Kidney Int Rep. 2025 Aug;10(8). doi: 10.1016/j.ekir.2025.05.037.

Maillard, A., Feghoul, L., Lemiale, V., Mercier-Delarue, S., Demoule, A., Jaber, S., Klouche, K., Kouatchet, A., Argaud, L., Barbier, F., Bigé, N., Moreau, A. S., Canet, E., Pène, F., Salmona, M., Mokart, D., Azoulay, E. and LeGoff, J. Clinical significance of respiratory torque teno virus in immunocompromised patients with acute respiratory failure Clin Microbiol Infect. 2025 Aug 23;doi: 10.1016/j.cmi.2025.07.035.

Mangiacapra, F., Paolucci, L., De Bruyne, B., Rioufol, G., Hahn, J. Y., Chen, S. L., Koo, B. K., Tonino, P. A. L., van ‘t Veer, M., Motreff, P., Angoulvant, D., Lee, J. M., Hwang, D., Yang, S., Pijls, N. H. J. and Barbato, E. Fractional flow reserve vs angiography to guide percutaneous coronary intervention: an individual patient data meta-analysis Eur Heart J. 2025 Aug 20;doi: 10.1093/eurheartj/ehaf504.

Maragliano, R., Perrot, A., Loget, P., Combescure, C., Belhomme, N., Faoucher, M., Dubourg, C., Fradin, M. and Collardeau-Frachon, S. Characterization of autopsy findings including multivisceral glomeruloid vascular bodies in hereditary thrombotic thrombocytopenic purpura with two new variants in ADAMTS13 gene Virchows Arch. 2025 Aug 4;doi: 10.1007/s00428-025-04200-8.

Mazighi, M., Lambert, J., Gory, B., Seners, P., Calvière, L., Cho, T. H., Aghetti, A., Pasi, M., Boulouis, G., Lapergue, B., Consoli, A., Turc, G., Rouchaud, A., Wolff, V., Pop, R., Suissa, L., Richard, S., Cordonnier, C., Arquizan, C., Costalat, V., Guedon, A., Cognard, C., Mameri, L., Escalard, S., Redjem, H., Smajda, S., Robichon, E., Al Raaisi, A., Boisseau, W., Blanc, R., Maier, B., Boursin, P., Dubus, E., Desilles, J. P., Piotin, M., Rigon, M. R. and Olivot, J. M. Glenzocimab for reperfusion in the setting of endovascular therapy for brain infarction: GREEN study J Neurointerv Surg. 2025 Aug 27;doi: 10.1136/jnis-2025-023606.

Mendonça, C. R., Galindo, L. C. M., de Melo Silva, B. K. A., de Vasconcelos, B. H. A., de Araújo Bandeira, V. C., Hirabara, S. M., Morio, B. and de Vasconcelos, D. A. A. Maternal obesogenic diet causes insulin resistance by modulating insulin signaling pathways in peripheral tissues of offspring: a systematic review Life Sci. 2025 Aug 29;doi: 10.1016/j.lfs.2025.123947.

Omer, M. H., Shchendrygina, A., Ahmad, O., Saldarriaga, C., Goldfeder de Gracia, S., Alhussain, M., Echahidi, N., Kharabsheh, S. M., Ayoubi, F., Alghalayni, K., Alburaiki, J., Fadel, B., Bader, F., Skouri, H., Hamade, M., Załęska-Kocięcka, M., Guidetti, F., Mewton, N. and Mohty, D. Differences in the management of heart failure with preserved ejection fraction among physicians from Europe, the Middle East and North Africa: an international survey Open Heart. 2025 Aug 17;12(2). doi: 10.1136/openhrt-2025-003548.

Oubari, H., Boucher, F., Hashim, A., Dupuy, F., Shipkov, H. and Mojallal, A. Aesthetic Breast Reconstruction With De-epidermized Deep Inferior Epigastric Artery Perforator Flap and Thoracoabdominal Advancement Flap Plast Reconstr Surg Glob Open. 2025 Aug;13(8). doi: 10.1097/gox.0000000000006985.

Picaud, J. C., Claris, O., Gil-Campos, M., De La Cueva, I. S., Cornette, L., Alliet, P., Léké, A., Castanet, M., Piloquet, H., de Halleux, V., Mitanchez, D., Vandenplas, Y., Maton, P., Jochum, F., Olbertz, D., Policarpo, S. N., Lavalle, L., Fumero, C., Rodriguez-Garcia, P., Moll, J. M., Silva-Zolezzi, I., Zemrani, B., Hays, N. P., Sprenger, N. and Miranda-Mallea, J. Partially hydrolyzed, whey-based infant formula with six human milk oligosaccharides, B. infantis LMG11588, and B. lactis CNCM I-3446 is safe, well tolerated, and improves gut health: a staged analysis of a randomized trial Front Nutr. 2025 Aug;12(doi: 10.3389/fnut.2025.1628847.

Picaud, J. C., Hays, S. and Dananché, C. Commentary: Infusion line contamination in preterm neonates: impact of infusion line design, length, and use duration: the multicenter ChronoBIOline study Front Microbiol. 2025 Aug;16(doi: 10.3389/fmicb.2025.1581152.

Picaud, J. C., Reynolds, P. R., Clarke, P., van den Hooven, E., van Weissenbruch, M. M., van Lingen, R. A., Goedhart, A., Botma, A., Boettger, R., van Westering-Kroon, E., Fusch, C. and Hascoet, J. M. A novel human milk fortifier supports adequate growth in very low birth weight infants: a non-inferiority randomised controlled trial Arch Dis Child Fetal Neonatal Ed. 2025 Aug 19;110(5). doi: 10.1136/archdischild-2024-327282.

Procopi, N., Zeitouni, M., Kerneis, M., Cayla, G., Ferrari, E., Range, G., Puymirat, E., Delarche, N., Guedeney, P., Beygui, F., Desprets, L., Georges, J. L., Bochaton, T., Schiele, F., Ducrocq, G., Hauguel-Moreau, M., Dumaine, R., Slama, M. S., Payot, L., El Kasty, M., Aacha, K., Diallo, A., Girerd, X., Vicaut, E., Silvain, J. and Montalescot, G. Beta-blocker interruption effects on blood pressure and heart rate after myocardial infarction: the AβYSS trial Eur Heart J. 2025 Aug 1;46(29). doi: 10.1093/eurheartj/ehaf170.

Quennepoix, M., Koppe, L., Bevier, A., Barba, C., Espi, M., Barnel, C., Fouque, D. and Novel-Catin, E. Comparison of different heparin-free dialysis methods Nephrol Dial Transplant. 2025 Aug 29;40(9). doi: 10.1093/ndt/gfaf082.

Rivet, V., Joseph, A., Arrestier, R., Calvet, L., Moreau, A. S., Bureau, C., Argaud, L., Gabarre, P., Zuber, B., Raphalen, J. H., Pons, S., Clere-Jehl, R. and Zafrani, L. Immunosuppressive therapy management during sepsis in kidney transplant recipients: a prospective multicenter study Ann Intensive Care. 2025 Aug 10;15(1). doi: 10.1186/s13613-025-01523-2.

Robert, M., Poghosyan, T., Romain-Scelle, N., Czernichow, S., Delaunay, D., Sterkers, A., Khamphommala, L., Lazzati, A., Blanchard, C., Caiazzo, R., Pattou, F. and Disse, E. Efficacy and safety of single-anastomosis duodeno-ileal bypass with sleeve gastrectomy versus Roux-en-Y gastric bypass in France (SADISLEEVE): results of a randomised, open-label, superiority trial at 2 years of follow-up Lancet. 2025 Aug 23;406(10505). doi: 10.1016/s0140-6736(25)01070-0.

Sellier-Leclerc, A. L., Magen, D., Shasha-Lavsky, H., Simkova, E., Devresse, A., Guebre-Egziabher, F., Michael, M., Lieske, J. C., Frishberg, Y., Bakkaloglu, S. A., Mourani, C., Saqan, R., Singer, R., Guzzo, I., Makarova, N., Willey, R., Kaspar, C., Gansner, J. M. and Groothoff, J. W. Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1: 24-Month Follow-up of the Phase 3 ILLUMINATE-C Trial Am J Kidney Dis. 2025 Aug;86(2). doi: 10.1053/j.ajkd.2025.01.016.

Tinggaard, A. B., Toupin, S., Dillinger, J. G., Delmas, C., Trimaille, A., Bouleti, C., Schurtz, G., Fauvel, C., Dib, J. C., Andrieu, S., Roubille, F., Levasseur, T., Bonnet, G., Boukhris, M., Bochaton, T., Roule, V., Delsarte, L., Boccara, A., Albert, F., Boccara, F., Puymirat, E., Wiggers, H., Mebazaa, A., Cohen-Solal, A., Chousterman, B. G., Henry, P. and Pezel, T. Predicting 1-year heart failure hospitalization and mortality post-discharge from the intensive cardiac care unit ESC Heart Fail. 2025 Aug;12(4). doi: 10.1002/ehf2.15140.

Voiriot, G., Argaud, L., Cohen, Y., Tuffet, S., Chauvelot, L., Souweine, B., Klouche, K., Reignier, J., Schwebel, C., Rouzé, A., Mekontso Dessap, A., Bohé, J., Megarbane, B., Carvelli, J., Navellou, J. C., Gibot, S., Maury, É., Dellamonica, J., Dequin, P. F., Dessajan, J., Armand-Lefèvre, L., Vandenesch, F., Verdet, C., Durand Zaleski, I., Bérard, L., Rousseau, A., Tabassome, S., Fartoukh, M. and Timsit, J. F. Combined use of a multiplex PCR and serum procalcitonin to reduce antibiotic exposure in critically ill patients with community-acquired pneumonia: the MULTI-CAP randomized controlled trial Intensive Care Med. 2025 Aug;51(8). doi: 10.1007/s00134-025-08014-9.

Wagner, S., Girerd, N., Lemonnier, C., Yena, K., Lamiral, Z., Duarte, K., Merkling, T., Merckle, L., Bozec, E., Dougkas, A., Hoge, A., Guillaume, M., Rossignol, P., Nazare, J. A., Vors, C., Boivin, J. M. and Michalski, M. C. Saturated fat from dairy sources and cardio-metabolic health: insights from the STANISLAS cohort Eur J Nutr. 2025 Aug 30;64(6). doi: 10.1007/s00394-025-03763-1.

 

Septembre 2025

Bidar, F., Chardon, N., Darnajoux, Q., Petit, M., Fellahi, J. L., Aubrun, F., Argaud, L., Richard, J. C., Dailler, F., Wallet, F. and Rimmelé, T. Clinical and biological profiles associated with the time of occurrence of citrate accumulation in patients receiving continuous renal replacement therapy Crit Care. 2025 Sep 26;29(1). doi: 10.1186/s13054-025-05648-5.

Boccalini, S., Fourrier, C., Si-Mohamed, S., Bonnefoy-Cudraz, E., Bochaton, T., Boussel, L., Vlachomitrou, A., Wiemker, R. and Douek, P. Appearance of myocarditis lesions on spectral CT arterial acquisitions and correlation with edema on MRI Eur Radiol Exp. 2025 Sep 11;9(1). doi: 10.1186/s41747-025-00613-x.

Bonnet-Chateau, J., Collin, M., Gilles, V., Dautricourt, S., Makaroff, Z., Coste, M. H., Gilbert, T., Falandry, C., Desestret, V., Moutet, C., Dauphinot, V. and Garnier-Crussard, A. [Frailty in dementia with Lewy bodies: relationship with clinical features, intrinsic capacity and cognitive and functional decline] Geriatr Psychol Neuropsychiatr Vieil. 2025 Sep 1;23(3). doi: 10.1684/pnv.2025.1240.

Chene, G., Gjorgjievska-Delov, A., Atallah, A., Ohannessian, A., Cerruto, E. and Nohuz, E. How to detect and remove deep or nonpalpable contraceptive implants ? A technical note J Gynecol Obstet Hum Reprod. 2025 Sep 15;54(10). doi: 10.1016/j.jogoh.2025.103036.

Chiva-Blanch, G., Liehn, E., Andreadou, I., Barc, J., Brundel, B., Davidson, S. M., Elliott, P., Evans, P. C., Giricz, Z., Gladka, M., Gollmann-Tepeköylü, C., Kleinbongard, P., Krieg, T., Linde, C., Lüscher, T. F., Guzik, T., Maguy, A., McDonagh, T., Paillard, M., Parma, R., Pesce, M., Pompilio, G., Rubini, M., Streckfuss-Bömeke, K., Thielmann, M., Tocchetti, C. G., Van Linthout, S., Vardas, P., Vranckx, P., Wojta, J. and Perrino, C. Importance of basic science and research training for the future generation of cardiologists Eur Heart J. 2025 Sep 25;doi: 10.1093/eurheartj/ehaf738.

Colson, P. H., Gaudriot, B., Provenchère, S., Rozec, B., Cholley, B., Mauriat, P., Sénard, M. and Fellahi, J. L. Half-Dose versus Full Dose of Aprotinin in Cardiac Surgery: A Post-hoc Analysis of the Aprotinin European Registry Eur J Cardiothorac Surg. 2025 Sep 1;67(9). doi: 10.1093/ejcts/ezaf260.

Contou, D., Painvin, B., Daubin, D., Orieux, A., Pirollet, H., Cour, M., Sarton, B., Gauvrit, M., Taillantou-Candau, M., Lepoutre, P., Louis, G., Bruneel, F., Teiten, C., Vincendeau, M., Giry, M., Legay, F., Coudroy, R., Puig, O., Bay, P., Schnell, G., Ledoux, G., Sonneville, R., Reuter, D., Valette, X., Szychowiak, P., Dufour, N., Urbina, T., Plantefève, G. and de Prost, N. Hemodynamic and neurological presentations of invasive meningococcal disease in adults: a nationwide study across 100+ French ICUs : The RETRO-MENINGO study Intensive Care Med. 2025 Sep;51(9). doi: 10.1007/s00134-025-08043-4.

Duquerois, A. S., Martinez-Vinson, C., Loppinet, T., Restier, L., Poinsot, P., Portefaix, A., Heissat, S., Peretti, N., Caron, N. and Duclaux-Loras, R. A series of pediatric patients with inflammatory bowel disease switching from intravenous to subcutaneous infliximab maintenance therapy Clin Res Hepatol Gastroenterol. 2025 Sep-Oct;49(8). doi: 10.1016/j.clinre.2025.102680.

Glorieux, G., Burtey, S., Evenepoel, P., Jankowski, J., Koppe, L., Masereeuw, R. and Vanholder, R. A guide to uraemic toxicity Nat Rev Nephrol. 2025 Sep 23;doi: 10.1038/s41581-025-01006-4.

Godet, M., Meugnier, E., Vitalis, O., Bendridi, N., Vieille-Marchiset, A., Vega, N., Benoit, B., Pinteur, C., Rainteau, D., Cheillan, D., Michalski, M. C., Chikh, K. and Vidal, H. Evaluation of the effects of metformin on gut functions and microbiota and their contribution to improving glucose tolerance in diabetic mice Mol Metab. 2025 Sep 29;102(doi: 10.1016/j.molmet.2025.102263.

Gomez, M. V. P., Costea, G. C., Claus, L., Gall, E. C., van Eerde, A. M., Lemoine, S., Groothoff, J., Levtchenko, E., Klein, L., Pape, L., Müller, R. U. and Liebau, M. C. Transition of patients with hereditary nephropathies from pediatric to adult care Nephrol Dial Transplant. 2025 Sep 10;doi: 10.1093/ndt/gfaf186.

Guerraoui, A., Haesebaert, J., Subtil, F., Hanf, W., Pelletier, C., Jullien, P., Villar, E., Mezaache, S., Filancia, A., Fauvel, J. P., Mariat, C., Granal, M., Guebre-Egziabher, F., Couchoud, C., Caillette-Beaudoin, A. and Fouque, D. Concordance of symptoms perceived by patients receiving haemodialysis and those reported by nurses and nephrologists: a cross-sectional, multicentre, observational study using the REIN registry Clin Kidney J. 2025 Sep;18(9). doi: 10.1093/ckj/sfaf239.

Guillermou, H., Mercier, G., Bonnefoy-Cudraz, E., Delmas, C. and Roubille, F. Evolution of intensive cardiac care units over the past decade: A France nationwide observational database study comparing recent trends (2014-2023) Arch Cardiovasc Dis. 2025 Sep;118(8-9). doi: 10.1016/j.acvd.2025.02.013.

Hakkar, R., Brun, C. E., Leblanc, P., Meugnier, E., Berger-Danty, E., Blanc-Brude, O., Tacconi, S., Jalabert, A., Reininger, L., Pesenti, S., Calzada, C., Gache, V., Vasan, S. B., Pichon, J., Larcher, T., Errazuriz-Cerda, E., Cassin, C., Sung, B. H., Weaver, A., Bongiovanni, A., Rouger, K., de Barros, J. P., Bouzakri, K. and Rome, S. Sphingolipids in Extracellular Vesicles Released From the Skeletal Muscle Plasma Membrane Control Muscle Stem Cell Fate During Muscle Regeneration J Extracell Vesicles. 2025 Sep;14(9). doi: 10.1002/jev2.70164.

Jaëck, M., El Bèze, N., Dillinger, J. G., Trimaille, A., Chaussade, A. S., Thuaire, C., Delmas, C., Boccara, A., Roule, V., Millischer, D., Thevenet, E., Meune, C., Stevenard, M., Maitre Ballesteros, L., Grinberg, N., Gonçalves, T., Baudet, M., El Ouahidi, A., Swedsky, F., Lattuca, B., Hauguel-Moreau, M., Schurtz, G., Dupasquier, V., Bochaton, T., Puymirat, E., Toupin, S., Henry, P., Pezel, T. and Charbonnel, C. Psychoactive drug use and prognosis in patients with cancer presenting with acute cardiovascular disease Arch Cardiovasc Dis. 2025 Sep;118(8-9). doi: 10.1016/j.acvd.2025.03.122.

Laigle, V., Thomas, L., Picart, T., Tommasino, E., Dumot, C., d’Hombres, A., Feuvret, L., Jupin-Delevaux, E., Gamondès, D., Hermier, M., Cotton, F., Honnorat, J., Ducray, F., Berthezène, Y. and Bani-Sadr, A. Diagnostic value of centrally restricted diffusion in differentiating radiation necrosis from tumor progression in brain metastases: A single-center observational study J Neuroradiol. 2025 Sep 5;52(6). doi: 10.1016/j.neurad.2025.101386.

Laiola, M., Koppe, L., Larabi, A., Thirion, F., Lange, C., Quinquis, B., David, A., Le Chatelier, E., Benoit, B., Sequino, G., Chanon, S., Vieille-Marchiset, A., Herpe, Y. E., Alvarez, J. C., Glorieux, G., Krukowski, H., Huys, G. R., Raes, J., Fouque, D., Massy, Z. A., Ehrlich, S. D., Stengel, B. and Wagner, S. Toxic microbiome and progression of chronic kidney disease: insights from a longitudinal CKD-Microbiome Study Gut. 2025 Sep 8;74(10). doi: 10.1136/gutjnl-2024-334634.

Lefebvre, R., Rousseaux, T., Bendridi, N., Chanon, S., Arquier, D., Humbert, A., Bertocchini, N., Pillot, B., Meugnier, E., Vieille-Marchiset, A., Nawrot, M., Pinteur, C., Ayciriex, S., Loomba, R., Rieusset, J. and Caussy, C. N-acetyl-phenylalanine induces hepatic steatosis in MASLD by disrupting ER-mitochondria calcium coupling and mitochondrial lipid oxidation bioRxiv. 2025 Sep 26;doi: 10.1101/2025.09.24.678188.

Lemiale, V., Resche-Rigon, M., Zerbib, Y., Mokart, D., De Prost, N., Wallet, F., Perez, P., Kouatchet, A., Argaud, L., Decavèle, M., Pène, F., Seguin, A., Megarbane, B., Calvet, L., Picard, M., Rigault, G., Mariotte, E., Bouadma, L., Theodose, I., Tamion, F., Klouche, K., Colin, G., Nyunga, M., Moreau, A. S. and Azoulay, E. Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial Lancet Respir Med. 2025 Sep;13(9). doi: 10.1016/s2213-2600(25)00125-0.

Leone, G., Ucakar, B., Perros, F., Frédérick, R. and Vanbever, R. Synthesis and in vitro evaluation of polyethylene glycol-treprostinil conjugates for sustained local delivery in pulmonary arterial hypertension Eur J Pharm Sci. 2025 Sep 21;214(doi: 10.1016/j.ejps.2025.107287.

Messika-Zeitoun, D., Chu, M. W. A., Bouchard, D., Le Tourneau, T., Ternacle, J., Demers, P., Guo, L., Fu, A. Y. N., Dib, J. C., Lam, C., Sokolov, T., Anselmi, A., Tchétché, D., Brault Meslin, O., Goutondji, A., Lavie-Badie, Y., Seknadji, P., Coisne, A., Arangalage, D., Bernard, A., Manian, U., Kass, M., Fiore, A., Maudiere, A., Bohbot, Y., Seemann, A., Hammoudi, N., Bière, L., Leroux, P. Y., Forcillo, J., Jeu, A., Elegamandji, B., Selton-Suty, C., Gilard, M., Bouleti, C., Arshad, O., Legare, J. F., Si Moussi, T., Ye, J., Sportouch, C., Bittira, B., Munte, L., Bauer, F., Ong, G., Fatehi Hassanabad, A., Bernick, J., Wells, G. A., Gauda, R., Iung, B., Kent, W. D. T., Obadia, J. F. and Dreyfus, J. Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry Circulation. 2025 Sep 30;152(13). doi: 10.1161/circulationaha.124.073674.

Najdi, N., Jung, C., Castañeda-Gutiérrez, E., Michalski, M. C., Beraud, V., Peretti, N., Jung, C., Belaïche, M., Bouziane-Nedjadi, K., Clouzeau, H., Coopman, S., De L’Hermuzière, C., Degas, V., Fabre, A., Garcette, K., Lalanne, A., Ley, D., Martinez-Vinson, C., Piloquet, H., Scheers, I. and Peretti, N. Lipid intake in infants from birth to 3 years old: review of current guidelines and knowledge gaps Nutr Res Rev. 2025 Sep 29;doi: 10.1017/s095442242510019x.

Paillard, M., Abdellatif, M., Andreadou, I., Bär, C., Bertrand, L., Brundel, B., Chiva-Blanch, G., Davidson, S. M., Dawson, D., Di Lisa, F., Evans, P., Giricz, Z., Hausenloy, D. J., Kleinbongard, P., Lezoualc’h, F., Liehn, E., Maack, C., Maguy, A., Murphy, E., Perrino, C., Pesce, M., Rainer, P. P., Streckfuss-Bömeke, K., Thielmann, M., Tian, R., Tocchetti, C. G., Van Der Velden, J., Van Linthout, S., Zacchigna, S. and Krieg, T. Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function Eur J Heart Fail. 2025 Sep;27(9). doi: 10.1002/ejhf.3674.

Raillon, L. A., Florens, N., Payelle, F., Martin, M., Soulère, L., Yi, D., Simon-Onfroy, Z., Chambert, S., Legras, M., Chardon, L., Glorieux, G., Guebre-Egziabher, F. and Soulage, C. O. Medium chain fatty acids are potent binding competitors to improve protein-bound uremic toxin clearance during hemodialysis Kidney Int. 2025 Sep;108(3). doi: 10.1016/j.kint.2025.06.004.

Russell-Hallinan, A., Karuna, N., Lezoualc’h, F., Matullo, G., Baker, H., Bernard, M., Devaux, Y., Badimon, L., Vilahur, G., Rieusset, J., Derumeaux, G. A. and Watson, C. J. Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy Diabetes Metab Res Rev. 2025 Sep;41(6). doi: 10.1002/dmrr.70081.

Sonneville, R., Couffignal, C., Souweine, B., Demiri, S., Terzi, N., Bruneel, F., Mekontso Dessap, A., Martin, M., Marois, C., Bailly, P., Kouatchet, A., Voiriot, G., Reizine, F., Benghanem, S., Louis, G., Conrad, M., Hraiech, S., Thille, A. W., Navellou, J. C., Contou, D., Bourcier, S., Tran, M., Dailler, F., Argaud, L., Cerf, C., Guidet, B., Roux, D., Kerhuel, L., Van Der Meersch, G., Nseir, S., Joseph, A., Da Silva, D., Beuret, P., Sarton, B., Estellat, C., Godard, V., Honnorat, J., Lavallée, P. C., Esposito-Farèse, M. and Timsit, J. F. Outcomes of Critically Ill Adult Patients With Acute Encephalitis JAMA Netw Open. 2025 Sep 2;8(9). doi: 10.1001/jamanetworkopen.2025.32478.

Tournebize, C., De Mul, A., Abid, N., Portefaix, A., Pacaud, S., Schleef, M., Derain-Dubourg, L., Rouviere, O. and Lemoine, S. Medullary sponge kidney: in-depth phenotyping for a better understanding of functional and structural abnormalities J Nephrol. 2025 Sep 19;doi: 10.1007/s40620-025-02413-3.

Younossi, Z. M., Paik, J. M., Lazarus, J. V., Burra, P., Eguchi, Y., Tacke, F., Crespo, J., Villela-Nogueira, C. A., Brennan, P. N., Al-Omar, H. A., Romero-Gomez, M., Caussy, C., Pessoa, M. G., Cusi, K., Roden, M., Takahashi, H., Gastaldelli, A., Schattenberg, J. M., Oliveira, C. P., Kawaguchi, T., Eguchi, Y., Boursier, J., Abaalkhail, F., Tomlinson, J. W., Allen, A. M., Wai-Sun Wong, V., Bugianesi, E., Newsome, P. N., Calleja, J. L., Brachowicz, N., Agirre-Garrido, L., Maya-Miles, D., Razack, H. I. A., Mark, H. E., Nader, A., Battistella, S., Margier, J., Risso, A., Stepanova, M., Nader, F., Henry, L., Castera, L. and Alqahtani, S. A. Projected Global Clinical, Humanistic, and Economic Impact of Metabolic Dysfunction-Associated Steatohepatitis (MASH): The Cost of Inaction Based on Data From Nine Countries Clin Gastroenterol Hepatol. 2025 Sep 8;doi: 10.1016/j.cgh.2025.09.002.