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Compétences et expertises

• Physiologiste cellulaire

Points forts

• ischémie-reperfusion ; cardioprotection ; nephroprotection; mort cellulaire ; sirtuines ; hypothermie thérapeutique ; conservation d’organe.

Prix reçus

• Nov 2007: The Arnold Naimark Young Investigator Award for excellence in research accomplished in post-doctoral training – Institute of Cardiovascular Science Awards – Winnipeg – CANADA.

5 major publications:

• Baetz D, Haworth RS, Avkiran M, Feuvray D. “The extracellular signal-regulated kinase pathway regulates Na+-HCO3- cotransport activity in adult rat cardiomyocytes.” American Journal of Physiology 2002;
• Darmellah A , Baetz D, Prunier F, Tamareille S, Rücker-Martin C, Feuvray D. “Enhanced Na+/H+ exchange activity contributes to left-ventricular hypertrophy in type 2 diabetic GK rats: critical role of Akt.” Diabetologia. 2007
• Baetz D, Regula KM, Shaw J, Kothari S, Yurkova N, Kirshenbaum LA. “Nuclear factor-kappaB-mediated cell survival involves transcriptional silencing of the mitochondrial death gene BNIP3 in ventricular myocytes.” Circulation. 2005
• Bochaton T, Crola-Da-Silva C, Pillot B, Villedieu C, Ferreras L, Alam MR, Thibault H, Strina M, Gharib A, Ovize M & Baetz D. “Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D”. J Mol Cell Cardiol 2015
• Lemoine S, Pillot B, Augeul L, Normand G, Baetz D, Ovize M, Juillard L. “Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice”. PLOS ONE 2017. Aug 10; 12(8): e0182358.