Domaine de recherche
Pathologies cardiovasculaires
Compétences
Biologie cellulaire, Biochimie, Cytométrie en flux, Transparisation d’organes…
Financements obtenus ces cinq dernières années
- Fédération Française de Cardiologie, 2018-2020 :80000 euros (co-direction avec Michel Ovize)
- Bourse SFR Santé Lyon-Est, 2019-2020 : 4000 euros pour acquisition Imagerie à la plateforme CICLE (co-direction avec Gabriel Bidaux)
- Bourse Fondation de l’avenir 40000 euros = 2020-2021 (co-direction avec Mélanie Paillard)
5 major publications:
Thomas Bochaton, Simon Leboube, Alexandre Paccalet, Claire Crola Da Silva et al.Impact of age on systemic inflammatory profile of patients with ST-segment elevation myocardial infarction and acute ischemic stroke. Stroke. 2022 Mar31;101161STROKEAHA121036806. doi:10.1161/STROKEAHA.121.036806. Online ahead of print
Stevic N, Maalouf J, Argaud L, Gallo-Bona N, Lo Grasso M, Gouriou Y, Gomez L, Crola Da Silva C et al. Cooling uncouples differentially ROS production from respiration and Ca homeostasis dynamic in brain and heart mitochondria. Cells. 2022 Mar 14;11(6):989. doi: 10.3390/cells11060989.PMID: 35326440 Free PMC article.
Alexandre Paccalet, Claire Crola Da Silva, Laura Mechtouff et al. Serum soluble tumor necrosis factor receptors 1 and 2 are early prognosis markers after ST-segment elevation myocardial infarction. Front Pharmacol. 2021 Sep 1;12:656928. doi: 10.3389/fphar.2021.656928. eCollection 2021
Alexandre Paccalet, Nolwenn Tessier, Mélanie Paillard, Lucille Païta Ludovic Gomez, Noëlle Gallo Bona, Christophe Chouabe, Christelle Léon, Sally Badawi, Zeina Harhous, Michel Ovize and Claire Crola Da Silva. An innovative sequence of hypoxia-reoxygenation on adult mouse cardiomyocytes in suspension to perform multilabeling analysis by flow cytometry. Am J Physiol Cell Physiol.2020 Feb 1 ;318(2) : C439-C447.doi :10.1152/ajpcell.00393.2019
Simon Leboube, Alexandre Paccalet, Claire Crola Da Silva et al. Soluble C-Met as a biomarker of clinical outcomes after STEMI. J Am Coll Cardiol. 2021 May 11;77(18):2348-2350. doi: 10.1016/j.jacc.2021.03.015.