Centre de Recherche en Nutrition Humaine - Rhône-Alpes

Publications 2025

Berthomé A, Antoine T, Meiller L, Govers R, Guichard P, Sabran C, Gonzalez T, Nowicki M, Bordat C, Borel P, Grino M, Sauvinet V, Reboul E. Perinatal vitamin A excess impacts vitamin A and lipid metabolism in rat offspring. Sci Rep. 2025 Oct 7;15(1):34987. doi: 10.1038/s41598-025-18896-w. PMID: 41057405; PMCID: PMC12504743

Godet M, Meugnier E, Vitalis O, Bendridi N, Vieille-Marchiset A, Vega N, Benoit B, Pinteur C, Rainteau D, Cheillan D, Michalski MC, Chikh K, Vidal H. Evaluation of the effects of metformin on gut functions and microbiota and their contribution to improving glucose tolerance in diabetic mice. Mol Metab. 2025 Sep 29:102263. doi: 10.1016/j.molmet.2025.102263. Epub ahead of print. PMID: 41033655.

Xia LLCH, Girerd N, Lamiral Z, Duarte K, Merckle L, Leroy C, Nazare JA, Van Den Berghe L, Seconda L, Hoge A, Guillaume M, Laville M, Rossignol P, Boivin JM, Wagner S. Association between ultra-processed food consumption and inflammation: insights from the STANISLAS cohort. Eur J Nutr. 2025 Feb 17;64(2):94. doi: 10.1007/s00394-025-03607-y. PMID: 39960649.

Hornero-Ramirez H, Morisette A, Marcotte B, Penhoat A, Lecomte B, Panthu B, Lessard Lord J, Thirion F, Van-Den-Berghe L, Blond E, Simon C, Caussy C, Feugier N, Doré J, Sanoner P, Meynier A, Desjardins Y, Pilon G, Marette A, Cani PD, Laville M, Vinoy S, Michalski MC, Nazare JA. Multifunctional dietary approach reduces intestinal inflammation in relation with changes in gut microbiota composition in subjects at cardiometabolic risk: the SINFONI project. Gut Microbes. 2025 Dec;17(1):2438823. doi: 10.1080/19490976.2024.2438823. Epub 2024 Dec 22. PMID: 39710576.

Connan C, Fromentin S, Benallaoua M, Alvarez AS, Pons N, Quinquis B, Morabito C, Nazare JA, Borezée-Durant E; Le French Gut Consortium; Haimet F, Ehrlich SD, Valeille K, Cavezza A, Blottière H, Veiga P, Almeida M, Doré J, Benamouzig R. Associations Among Diet, Health, Lifestyle, and Gut Microbiota Composition in the General French Population: Protocol for the Le French Gut – Le Microbiote Français Study. JMIR Res Protoc. 2025 May 13;14:e64894. doi: 10.2196/64894. Erratum in: JMIR Res Protoc. 2025 Jul 14;14:e80127. doi: 10.2196/80127. PMID: 40358997; PMCID: PMC12117270.

Prioux C, Wagner S, Fézeu LK, Deschamps V, Verdot C, Baudry J, Touvier M, Hercberg S, Nazare JA, Hoge A, Ferreira JP, Rossignol P, Girerd N, Tatulashvili S, Kesse-Guyot E, Allès B. Cross-sectional associations between healthy and unhealthy plant-based diets and metabolic syndrome in three distinct French populations: a meta-analysis. Br J Nutr. 2025 Mar 3;133(7):1-17. doi: 10.1017/S0007114525000376. Epub ahead of print. Erratum in: Br J Nutr. 2025 Aug 14;134(3):263-264. doi: 10.1017/S0007114525103978. PMID: 40026144; PMCID: PMC12198348.

Wagner S, Girerd N, Lemonnier C, Yena K, Lamiral Z, Duarte K, Merkling T, Merckle L, Bozec E, Dougkas A, Hoge A, Guillaume M, Rossignol P, Nazare JA, Vors C, Boivin JM, Michalski MC. Saturated fat from dairy sources and cardio-metabolic health: insights from the STANISLAS cohort. Eur J Nutr. 2025 Aug30;64(6):267. doi: 10.1007/s00394-025-03763-1. PMID: 40884570.

Ritsch N, Guyot E, Domingie S, Disse E, Iceta S, Nazare JA, Dougkas A. Food choices, microstructure of ingestive behavior and sensory perceptions after bariatric surgery in women: A cross-sectional study. Appetite. 2025 Feb 1;206:107800. doi: 10.1016/j.appet.2024.107800. Epub 2024 Dec 1. PMID: 39626828.

Connan C, Fromentin S, Benallaoua M, Alvarez AS, Pons N, Quinquis B, Morabito C, Nazare JA, Borezée-Durant E; Le French Gut Consortium; Haimet F, Ehrlich SD, Valeille K, Cavezza A, Blottière H, Veiga P, Almeida M, Doré J, Benamouzig R. Correction: Associations Among Diet, Health, Lifestyle, and Gut Microbiota Composition in the General French Population: Protocol for the Le French Gut – Le Microbiote Français Study. JMIR Res Protoc. 2025 Jul 14;14:e80127. doi: 10.2196/80127. Erratum for: JMIR Res Protoc. 2025 May 13;14:e64894. doi: 10.2196/64894. PMID: 40658453; PMCID: PMC12304775.

El Deghel N, Rapinski M, Duboz P, Raymond R, Davy D, Durães N, Dendievel AM, Ferreira da Silva E, Lopez PJ, Vaccher V, Vénisseau A, Nazare JA, Badin AL, Bedell JP. Persistent organic pollutants in food systems: A comparative study across four contrasting socio-ecosystems: Portugal, Senegal, French Guiana, and Guadeloupe. Food Chem. 2025 Nov 30;493(Pt 2):145766. doi: 10.1016/j.foodchem.2025.145766. Epub 2025 Jul 30. PMID: 40774192.

Prioux C, Wagner S, Fézeu LK, Deschamps V, Verdot C, Baudry J, Touvier M, Hercberg S, Nazare JA, Hoge A, Ferreira JP, Rossignol P, Girerd N, Tatulashvili S, Kesse-Guyot E, Allès B. Cross-sectional associations between healthy and unhealthy plant-based diets and metabolic syndrome in three distinct French populations: a meta-analysis – ERRATUM. Br J Nutr. 2025 Aug 14;134(3):263-264. doi: 10.1017/S0007114525103978. Epub 2025 Aug 6. Erratum for: Br J Nutr. 2025 Mar 03:1-17. doi: 10.1017/S0007114525000376. PMID: 40764065.

Publications 2024

Aubin A, Hornero-Ramirez H, Ranaivo H, Simon C, Van Den Berghe L, Favier NF, Dussous I, Roger L, Laville M, Béra-Maillet C, Doré J, Caussy C, Nazare JA. Assessing metabolic flexibility response to a multifibre diet: a randomised- controlled trial. J Hum Nutr Diet. 2024 Oct;37(5):1186-1196. doi: 10.1111/jhn.13350. Epub 2024 Aug 13. PMID: 39138876.

Agbo LD, Girerd N, Lamiral Z, Duarte K, Bozec E, Merckle L, Hoge A, Guillaume M, Laville M, Nazare JA, Rossignol P, Boivin JM, Wagner S. Dietary inflammatory potential and arterial stiffness in a French cohort: Insights from the STANISLAS study. Nutr Metab Cardiovasc Dis. 2024 Aug;34(8):1959-1967. doi: 10.1016/j.numecd.2024.03.022. Epub 2024 Mar 20. PMID: 38677885.

Teoli J, Chikh K, Jouini-Bouhamri R, Charriere S, Fabien N, Raverot V. When discordant insulin and C-peptide levels lead to a medical diagnosis in a patient with transient hypoglycemia: Varying degrees of interference of insulin-antibody complexes on three insulin immunoassays. Heliyon. 2024 Jul 2;10(13):e34009. doi: 10.1016/j.heliyon.2024.e34009. PMID: 39071705; PMCID: PMC11280251.

Chisbert M, Castell AL, Vinoy S, Nazare JA. The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance. Curr Opin Clin Nutr Metab Care. 2024 Jul 1;27(4):338-343. doi: 10.1097/MCO.0000000000001044. Epub 2024 Jun 6. PMID: 38836807; PMCID: PMC11155281.

Campos JO, Oliveira TLPSA, Vitalis O, Pereira JG, Nogueira IDCR, Santos GCJ, Chikh K, Leandro CG, Costa-Silva JHD, Pirola L. Association between Childhood Overweight and Altered Concentrations of Circulating Amino Acids. Nutrients. 2024 Jun 12;16(12):1843. doi: 10.3390/nu16121843. PMID: 38931197; PMCID: PMC11206240.

Tharrey M, Bohn T, Klein O, Bulaev D, Van Beek J, Nazare JA, Franco M, Malisoux L, Perchoux C. Local retail food environment exposure and diet quality in rural and urban adults: A longitudinal analysis of the ORISCAV-LUX cohort study. Health Place. 2024 May;87:103240. doi: 10.1016/j.healthplace.2024.103240. Epub 2024 Apr 8. PMID: 38593577.

Gibbons C, Beaulieu K, Almiron-Roig E, Navas-Carretero S, Martínez JA, O’Hara B, O’Connor D, Nazare JA, Le Bail A, Rannou C, Hardman C, Wilton M, Kjølbæk L, Scott C, Moshoyiannis H, Raben A, Harrold JA, Halford JCG, Finlayson G. Acute and two-week effects of neotame, stevia rebaudioside M and sucrose-sweetened biscuits on postprandial appetite and endocrine response in adults with overweight/obesity-a randomised crossover trial from the SWEET consortium. EBioMedicine. 2024 Apr;102:105005. doi: 10.1016/j.ebiom.2024.105005. Epub 2024 Mar 28. PMID: 38553262; PMCID: PMC11026940.

Hornero-Ramirez H, Aubin A, Michalski MC, Vinoy S, Caussy C, Nazare JA. Multifunctional dietary interventions, low-grade inflammation and cardiometabolic profile: a scoping review. Front Immunol. 2024 Feb 27;15:1304686. doi: 10.3389/fimmu.2024.1304686. PMID: 38476230; PMCID: PMC10927766.

Publications 2023

Beau A, Benoit B, Le Barz M, Meugnier E, Penhoat A, Calzada C, Pinteur C, Loizon E, Chanon S, Vieille-Marchiset A, Sauvinet V, Godet M, Laugerette F, Holowacz S, Jacouton E, Michalski MC, Vidal H. Inhibition of intestinal FXR activity as a possible mechanism for the beneficial effects of a probiotic mix supplementation  on lipid metabolism alterations and weight gain in mice fed a high fat diet. Gut Microbes. 2023 Dec;15(2):2281015. doi: 10.1080/19490976.2023.2281015. Epub 2023 Nov 20. PubMed [citation] PMID: 37985749, PMCID: PMC10730200

Perrier J, Nawrot M, Madec AM, Chikh K, Chauvin MA, Damblon C, Sabatier J, Thivolet CH, Rieusset J, Rautureau GJP, Panthu B. Human Pancreatic Islets React to Glucolipotoxicity by Secreting Pyruvate and Citrate. Nutrients. 2023 Nov 15;15(22):4791. doi: 10.3390/nu15224791. PMID: 38004183; PMCID: PMC10674605.

Demangeat A, Hornero-Ramirez H, Meynier A, Sanoner P, Atkinson FS, Nazare JA, Vinoy S. Complementary Nutritional Improvements of Cereal-Based Products to Reduce Postprandial Glycemic Response. Nutrients. 2023 Oct 17;15(20). pii: 4401. doi: 10.3390/nu15204401. PubMed [citation] PMID: 37892479, PMCID: PMC10609865

Chiriacò M, Nesti L, Flyvbjerg A, Golay A, Nazare JA, Anderwald CH, Mitrakou A, Bizzotto R, Mari A, Natali A. At any level of adiposity, relatively elevated leptin concentrations are associated with decreased insulin sensitivity. J Clin Endocrinol Metab. 2023 Aug 31. pii: dgad505. doi: 10.1210/clinem/dgad505. [Epub ahead of print] PubMed [citation] PMID: 37650623

Meiller L, Sauvinet V, Breyton AE, Ranaivo H, Machon C, Mialon A, Meynier A, Bischoff SC, Walter J, Neyrinck AM, Laville M, Delzenne NM, Vinoy S, Nazare JA. Metabolic signature of (13)C-labeled wheat bran consumption related to gut fermentation in humans: a pilot study. Eur J Nutr. 2023 Sep;62(6):2633-2648. doi: 10.1007/s00394-023-03161-5. Epub 2023 May 24. PubMed [citation] PMID: 37222787

Reynolds CM, Handjieva-Darlenska T, Nazare JA. Editorial: Women in nutrition and metabolism. Front Nutr. 2023 Mar 28;10:1181638. doi: 10.3389/fnut.2023.1181638. eCollection 2023. No abstract available. PubMed [citation] PMID: 37057064, PMCID: PMC10089368

Delage P, Ségrestin B, Seyssel K, Chanon S, Vieille-Marchiset A, Durand A, Nemeth A, Métairon S, Charpagne A, Descombes P, Hager J, Laville M, Vidal H, Meugnier E. Adipose tissue angiogenesis genes are down-regulated by grape polyphenols supplementation during a human overfeeding trial. J Nutr Biochem. 2023 Jul;117:109334. doi: 10.1016/j.jnutbio.2023.109334. Epub 2023 Mar 24. PubMed [citation] PMID: 36965784

Drareni K, Dougkas A, Giboreau A, Laville M, Souquet PJ, Nazare JA, Fournel P, Bensafi M. Loss of smell in lung cancer patients undergoing chemotherapy: Prevalence and relationship with food habit changes. Lung Cancer. 2023 Mar;177:29-36. doi: 10.1016/j.lungcan.2023.01.007. Epub 2023 Jan 12. PubMed [citation] PMID: 36701841

Puchkova-Sistac A, de Lauzon-Guillain B, Girerd N, Boivin JM, Bozec E, Mercklé L, Nazare JA, Laville M, Rossignol P, Wagner S. Association between eating behavior and 13-year cardiovascular damages in the initially healthy STANISLAS cohort. Eur J Prev Cardiol. 2023 Mar 1;30(4):349-357. doi: 10.1093/eurjpc/zwac287. PubMed [citation] PMID: 36626936

Thivolet C, Larger E, Cariou B, Renard E, Hanaire H, Benhamou PY, Guerci B, Mathiotte É, Chikh K. Dulaglutide and insulin microsecretion in people with type 1 diabetes (DIAMOND-GLP-1): A randomized double-blind placebo-controlled trial. Diabetes Metab. 2023 Mar;49(2):101433. doi: 10.1016/j.diabet.2023.101433. Epub 2023 Feb 11. PMID: 36781064.